追逐钟摆:阿片类药物和老年人的过去、现在和未来。

IF 4.9 3区 医学 Q1 GERIATRICS & GERONTOLOGY
Innovation in Aging Pub Date : 2025-05-06 eCollection Date: 2025-01-01 DOI:10.1093/geroni/igaf040
Fred Rottnek
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引用次数: 0

摘要

对急性和慢性阿片类药物治疗态度的转变深刻地影响了老年人疼痛的管理。从历史上看,阿片类药物已被认为对急性和癌症相关疼痛非常有效,但由于对成瘾、安全性和有效性的担忧,它们在慢性非癌症疼痛中的使用,特别是在老年人中,仍然存在争议。近几十年来,阿片类药物处方的增加与阿片类药物滥用、成瘾和过量死亡的急剧增加同时发生,促使人们重新审视处方做法和监管反应。本文追溯了阿片类药物政策和实践的历史“钟摆”,研究了老年人面临的独特挑战,包括对不良反应和多种药物的高度脆弱性,并强调了确保充分缓解疼痛和尽量减少伤害之间正在进行的辩论。它还探讨了最佳实践和新兴方法,如以患者为中心的护理和非阿片类药物治疗的整合,并呼吁建立一个平衡的、以证据为基础的框架,既能满足疼痛中的老年人的合法需求,又能满足减少阿片类药物相关危害的社会必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chasing the Pendulum: The Past, Present, and Future of Opioids and Older Adults.

The management of pain in older adults has been profoundly shaped by shifting attitudes toward acute and chronic opioid therapy. Historically, opioids have been recognized as highly effective for acute and cancer-related pain, but their use in chronic non-cancer pain, especially among older adults, remains controversial due to concerns about addiction, safety, and efficacy. Over recent decades, increased opioid prescribing has coincided with a dramatic rise in opioid misuse, addiction, and overdose deaths, prompting renewed scrutiny of prescribing practices and regulatory responses. This article traces the historical "pendulum" of opioid policy and practice, examines the unique challenges faced by older adults-including heightened vulnerability to adverse effects and polypharmacy-and highlights the ongoing debate between ensuring adequate pain relief and minimizing harm. It also explores best practices and emerging approaches, such as patient-centered care and the integration of non-opioid therapies, and calls for a balanced, evidence-based framework that addresses both the legitimate needs of older adults in pain and the societal imperative to reduce opioid-related harms.

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来源期刊
Innovation in Aging
Innovation in Aging GERIATRICS & GERONTOLOGY-
CiteScore
4.10
自引率
0.00%
发文量
72
审稿时长
15 weeks
期刊介绍: Innovation in Aging, an interdisciplinary Open Access journal of the Gerontological Society of America (GSA), is dedicated to publishing innovative, conceptually robust, and methodologically rigorous research focused on aging and the life course. The journal aims to present studies with the potential to significantly enhance the health, functionality, and overall well-being of older adults by translating scientific insights into practical applications. Research published in the journal spans a variety of settings, including community, clinical, and laboratory contexts, with a clear emphasis on issues that are directly pertinent to aging and the dynamics of life over time. The content of the journal mirrors the diverse research interests of GSA members and encompasses a range of study types. These include the validation of new conceptual or theoretical models, assessments of factors impacting the health and well-being of older adults, evaluations of interventions and policies, the implementation of groundbreaking research methodologies, interdisciplinary research that adapts concepts and methods from other fields to aging studies, and the use of modeling and simulations to understand factors and processes influencing aging outcomes. The journal welcomes contributions from scholars across various disciplines, such as technology, engineering, architecture, economics, business, law, political science, public policy, education, public health, social and psychological sciences, biomedical and health sciences, and the humanities and arts, reflecting a holistic approach to advancing knowledge in gerontology.
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