{"title":"疾病的二重性:阿尔茨海默病的困境通过鼻子和衰弱的镜头","authors":"Nikolaos Scarmeas, Adrián Noriega De La Colina","doi":"10.1093/brain/awaf239","DOIUrl":null,"url":null,"abstract":"Scarmeas & Noriega De La Colina use the ancient Greek concepts of nosos (biological disease) and asthenia (functional decline) to frame the shift in Alzheimer’s disease diagnosis from clinical symptoms to biomarkers, calling for better public understanding of both biological presence and lived experience.","PeriodicalId":9063,"journal":{"name":"Brain","volume":"10 1","pages":""},"PeriodicalIF":10.6000,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The duality of disease: the Alzheimer’s disease dilemma through the lens of nosos and asthenia\",\"authors\":\"Nikolaos Scarmeas, Adrián Noriega De La Colina\",\"doi\":\"10.1093/brain/awaf239\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Scarmeas & Noriega De La Colina use the ancient Greek concepts of nosos (biological disease) and asthenia (functional decline) to frame the shift in Alzheimer’s disease diagnosis from clinical symptoms to biomarkers, calling for better public understanding of both biological presence and lived experience.\",\"PeriodicalId\":9063,\"journal\":{\"name\":\"Brain\",\"volume\":\"10 1\",\"pages\":\"\"},\"PeriodicalIF\":10.6000,\"publicationDate\":\"2025-06-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/brain/awaf239\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/brain/awaf239","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
斯卡尔米斯,Noriega De La Colina利用古希腊的nosos(生物疾病)和asthenia(功能衰退)概念来阐述阿尔茨海默病的诊断从临床症状到生物标志物的转变,呼吁公众更好地理解生物存在和生活经历。
The duality of disease: the Alzheimer’s disease dilemma through the lens of nosos and asthenia
Scarmeas & Noriega De La Colina use the ancient Greek concepts of nosos (biological disease) and asthenia (functional decline) to frame the shift in Alzheimer’s disease diagnosis from clinical symptoms to biomarkers, calling for better public understanding of both biological presence and lived experience.
期刊介绍:
Brain, a journal focused on clinical neurology and translational neuroscience, has been publishing landmark papers since 1878. The journal aims to expand its scope by including studies that shed light on disease mechanisms and conducting innovative clinical trials for brain disorders. With a wide range of topics covered, the Editorial Board represents the international readership and diverse coverage of the journal. Accepted articles are promptly posted online, typically within a few weeks of acceptance. As of 2022, Brain holds an impressive impact factor of 14.5, according to the Journal Citation Reports.