伽玛刀治疗后前庭神经鞘瘤生长的预测因素：一项系统综述。

IF 4.4 2区医学 Q1 ONCOLOGY

Cancers Pub Date : 2025-06-14 DOI:10.3390/cancers17121993

Cheng Yang, Daniel Alvarado, Pawan Kishore Ravindran, Max E Keizer, Koos Hovinga, Martinus P G Broen, Danielle Eekers, Inge Compter, Henricus P M Kunst, Yasin Temel

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引用次数: 0

摘要

背景：GKRS在控制前庭神经鞘瘤生长方面具有较高的成功率，但治疗后仍有少数肿瘤生长。然而，只有少数研究调查了这种增长的预测因素。目的：探讨GKRS后前庭神经鞘瘤的生长决定因素。方法：本文分析了PubMed、EMBASE和Cochrane数据库2000 - 2024年间发表的文献。潜在的决定因素，包括年龄、性别、肿瘤体积、辐射剂量、肿瘤位置和影像学特征，已经被回顾。结论：我们发现初始肿瘤体积、预处理生长速率和成像ADC值可能预测GKRS后的生长。这些发现为进一步优化前庭神经鞘瘤的个性化治疗提供了参考。

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Predictors of Growth of Vestibular Schwannoma After Gamma Knife Treatment: A Systematic Review.

Background: GKRS shows a high success rate in controlling growth of vestibular schwannoma, but a small number of tumors still grow after treatment. However, only a few studies have investigated the predictive factors of this growth. Objective: Here, we aim to explore the growth determinants of vestibular schwannoma after GKRS. Methods: This paper has analyzed literature published between 2000 and 2024 from PubMed, EMBASE, and Cochrane databases. Potential determinants, including age, gender, tumor volume, radiation dose, tumor location, and imaging characteristics, have been reviewed. Conclusions: We have found that initial tumor volume, pretreatment growth rate, and imaging ADC value potentially predict growth after GKRS. These findings provide a reference for further optimizing personalized treatment in vestibular schwannoma care.

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来源期刊

Cancers Medicine-Oncology

CiteScore

8.00

自引率

9.60%

发文量

5371

审稿时长

18.07 days

期刊介绍： Cancers (ISSN 2072-6694) is an international, peer-reviewed open access journal on oncology. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.