Plasma renin activity, blood pressure and body weight during two years' oral contraception with two different low-estrogen combinations.

Body weight, systolic and diastolic blood pressure and plasma renin activity (PRA) were longitudinally followed in two groups of women during 2 years' oral contraception. One group (n = 10) received a combination of 0.150 mg levonorgestrel plus 0.030 mg ethinyloestradiol and the other (n = 10) a combination of 0.150 mg desogestrel plus 0.030 mg ethinyloestradiol. Three subjects discontinued the study due to relocation. No statistically significant changes occurred in any of the measured parameters.