在代谢网络建模的适当背景下重构目标函数的作用。

IF 7.7

Cell systems Pub Date : 2025-06-18 DOI:10.1016/j.cels.2025.101298

Mohammad Mazharul Islam, William Shao, Mariska Batavia, Roseanne M Ford, Bernhard O Palsson, Jens Nielsen, Costas D Maranas, Sang Yup Lee, Jason A Papin

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引用次数: 0

摘要

“目标函数”是代谢网络建模中的一个核心概念。它的使用使得对大数据的分析能够推动对细胞代谢的更深层次的理解。这篇评论重新定义了如何讨论目标函数以提高其价值并澄清代谢网络建模中的误解。

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Reframing the role of the objective function in its proper context for metabolic network modeling.

The "objective function" is a core concept in metabolic network modeling. Its use has enabled the analysis of large data to drive deeper understanding of cellular metabolism. This commentary reframes how the objective function is discussed to enhance its value and clarify misunderstandings in metabolic network modeling.

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Cell systems

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