打开肿瘤手术室:腹膜内热化疗联合术中电子束放疗治疗局部复发直肠癌伴腹膜转移。

IF 1.7 4区 医学 Q3 SURGERY
Y Salem, C T West, M West, S Jain, H Yano, J Smith, C Green, A Bateman, A Mirnezami
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引用次数: 0

摘要

尽管多模式治疗和手术技术取得了进步,但局部复发性直肠癌(LRRC)和腹膜转移(PM)仍然是外科医生和肿瘤学家面临的挑战。尽管腹膜疾病的全盆腔切除(TPE)和细胞减少手术(CRS)可以分别切除主要肿瘤块和宏观可见的腹膜扩散,但R1切除的局部复发和显微镜下腹膜疾病的腹膜复发仍然是关键问题。将根治性手术与肿瘤辅助治疗相结合,如术中电子束放疗(IOERT)和腹腔热化疗(HIPEC),可能会改善该领域的预后。然而,两者同时应用的报道很少。在这里,我们描述了一例LRRC与PM治疗与TPE和同时HIPEC和IOERT。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Opening the operating theatre to oncology: treatment of locally recurrent rectal cancer with peritoneal metastasis by simultaneous hyperthermic intraperitoneal chemotherapy and intraoperative electron beam radiotherapy.

Despite advances in multimodality therapies and surgical technique, locally recurrent rectal cancers (LRRC) and those with peritoneal metastasis (PM) remain challenging for surgeons and oncologists. Although total pelvic exenteration (TPE) and cytoreductive surgery (CRS) for peritoneal disease may enable removal of the main tumour mass and macroscopically visible peritoneal spread, respectively, local recurrence from an R1 resection, and peritoneal recurrence from microscopic peritoneal disease, remain key concerns. Combining radical surgery with oncological adjuncts such as intraoperative electron beam radiotherapy (IOERT), and hyperthermic intraperitoneal chemotherapy (HIPEC), may improve outcomes in this field. Nevertheless the application of both together is poorly reported. Here we describe a case of LRRC with PM treated with TPE and simultaneous HIPEC and IOERT.

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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
316
期刊介绍: The Annals of The Royal College of Surgeons of England is the official scholarly research journal of the Royal College of Surgeons and is published eight times a year in January, February, March, April, May, July, September and November. The main aim of the journal is to publish high-quality, peer-reviewed papers that relate to all branches of surgery. The Annals also includes letters and comments, a regular technical section, controversial topics, CORESS feedback and book reviews. The editorial board is composed of experts from all the surgical specialties.
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