{"title":"地衣内生微生物:生物医学领域的后起之星,值得更广泛的认识。","authors":"Jia-Na Zhu, Meng-Long Liu, Qiu-Hua He, Hai-Yan Ding","doi":"10.1080/10286020.2025.2501030","DOIUrl":null,"url":null,"abstract":"<p><p>Lichens are renowned for their ability to thrive in extreme environments and for producing unique metabolites with considerable bioactive potential. However, their medicinal value remains largely underexplored, primarily due to slow growth rates and habitat specificity. Notably, endolichenic microorganisms, particularly fungi, are the predominant producers of these bioactive compounds, which exhibit antimicrobial, antiviral, and anticancer properties. Investigating these microorganisms and their metabolites presents promising biomedical opportunities, underscoring the importance of sustainably utilizing lichen resources and discovering novel compounds. This paper reviews the diversity and bioactive potential of endophytic microorganisms in lichens, providing valuable insights for the exploration of natural resources.</p>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":" ","pages":"1-19"},"PeriodicalIF":1.3000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Endophytic microorganisms in lichen: rising stars in the biomedicine field deserving broader recognition.\",\"authors\":\"Jia-Na Zhu, Meng-Long Liu, Qiu-Hua He, Hai-Yan Ding\",\"doi\":\"10.1080/10286020.2025.2501030\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Lichens are renowned for their ability to thrive in extreme environments and for producing unique metabolites with considerable bioactive potential. However, their medicinal value remains largely underexplored, primarily due to slow growth rates and habitat specificity. Notably, endolichenic microorganisms, particularly fungi, are the predominant producers of these bioactive compounds, which exhibit antimicrobial, antiviral, and anticancer properties. Investigating these microorganisms and their metabolites presents promising biomedical opportunities, underscoring the importance of sustainably utilizing lichen resources and discovering novel compounds. This paper reviews the diversity and bioactive potential of endophytic microorganisms in lichens, providing valuable insights for the exploration of natural resources.</p>\",\"PeriodicalId\":15180,\"journal\":{\"name\":\"Journal of Asian Natural Products Research\",\"volume\":\" \",\"pages\":\"1-19\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-05-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Asian Natural Products Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/10286020.2025.2501030\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Asian Natural Products Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10286020.2025.2501030","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Endophytic microorganisms in lichen: rising stars in the biomedicine field deserving broader recognition.
Lichens are renowned for their ability to thrive in extreme environments and for producing unique metabolites with considerable bioactive potential. However, their medicinal value remains largely underexplored, primarily due to slow growth rates and habitat specificity. Notably, endolichenic microorganisms, particularly fungi, are the predominant producers of these bioactive compounds, which exhibit antimicrobial, antiviral, and anticancer properties. Investigating these microorganisms and their metabolites presents promising biomedical opportunities, underscoring the importance of sustainably utilizing lichen resources and discovering novel compounds. This paper reviews the diversity and bioactive potential of endophytic microorganisms in lichens, providing valuable insights for the exploration of natural resources.
期刊介绍:
The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures.
All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.