接种大肠杆菌产肠毒素菌株的断奶仔猪饲用乙酰化高直链淀粉和氧化锌的比较

IF 2.7 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE
Danica Evans, Bethany Bowring, Alison Collins, Julie Clarke, Jae-Cheol Kim, Josie Mansfield, John R Pluske
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引用次数: 0

摘要

断奶后腹泻(PWD)仍然是一些猪肉生产商面临的一个主要问题,限制或禁止使用抗菌化合物加剧了这一问题。乙酰化高直链玉米淀粉(HAMSA)将醋酸盐输送到大肠,可能降低肠道感染的严重程度,包括由大肠杆菌(E. coli)引起的感染。本研究研究了添加HAMSA和氧化锌(ZnO)对接种大肠杆菌F4产肠毒素菌株(F4- etec)的猪PWD和生产性能的影响。将72头断奶仔猪分为3个饲粮组:(1)对照组(不添加抗菌药物);(2)对照加3000 mg ZnO/kg;(3)对照加50 g HAMSA/kg。仔猪在断奶当天开始饲喂饲粮,在第5天和第6天接种F4-ETEC菌株,然后自由饲喂饲粮21 d。与其他饲粮相比,氧化锌饲粮的PWD发生率(χ2 = 0.035)和腹泻指数(P = 0.032)均最低,与血浆接触珠蛋白浓度(P = 0.010)相关,但HAMSA饲粮在断奶后第11天F4大肠杆菌:总大肠杆菌比值有交互作用趋势(P = 0.088)。在第3周,氧化锌和HAMSA的生长速度比对照组快(P = 0.009),食量也比对照组多(P = 0.048)。总体而言,氧化锌饲粮和HAMSA饲粮比对照组饲粮多吃约20% (P = 0.065),导致氧化锌饲粮和HAMSA饲粮在研究结束时比对照组猪重约10% (P = 0.064)。hamsa饲猪第3周的FCR较低(P = 0.044),总体上较低(P = 0.003)。饲喂HAMSA的猪没有表现出任何增加(P >;粪便短链脂肪酸或醋酸盐浓度差异0.05)。HAMSA对FCR的显著影响值得进一步研究,因为它可能提高肠内F4-ETEC感染后断奶后的生产效率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A comparison of feeding acetylated high-amylose maize starch and zinc oxide in weaned pigs experimentally inoculated with an enterotoxigenic strain of Escherichia coli
Post-weaning diarrhea (PWD) remains a major problem for some pork producers, exacerbated by restrictions or bans on the use of antimicrobial compounds. Acetylated high amylose maize starch (HAMSA) delivers acetate to the large bowel and may reduce the severity of enteric infections, including those caused by Escherichia coli (E. coli). This study examined the effects of HAMSA and zinc oxide (ZnO) supplementation on PWD and performance in pigs experimentally inoculated with an F4 enterotoxigenic strain of E. coli (F4-ETEC). Seventy-two weaned pigs were divided into 3 dietary groups: (1) control (no antimicrobial compounds); (2) control plus 3,000 mg ZnO/kg; (3) control plus 50 g HAMSA/kg. Pigs commenced diets on the day of weaning, were inoculated with an F4-ETEC strain on days 5 and 6, and were fed diets ad libitum for 21 days. The incidence of PWD (χ2 = 0.035) and the diarrhea index (P = 0.032) were both lowest, commensurate with a lower plasma haptoglobin concentration (P = 0.010), in pigs fed ZnO than pigs fed other diets, despite there being a trend for an interaction (P = 0.088) in pigs fed HAMSA to have a lower F4 E. coli:Total E. coli ratio on d 11 after weaning. Pigs fed ZnO and HAMSA grew faster (P = 0.009) and ate more (P = 0.048) in week 3 than control pigs. Overall, there was a trend (P = 0.065) for pigs fed the ZnO diet or HAMSA diet to eat ~ 20% more than those fed the control diet that resulted in a trend (P = 0.064) for ZnO- and HAMSA-fed pigs to weigh ~ 10% more than control-fed pigs at the end of the study. The HAMSA-fed pigs had a lower (P = 0.044) FCR in week 3, and overall (P = 0.003). Pigs fed HAMSA did not show any increase (P > 0.05) in their fecal short-chain fatty acid or acetate concentrations. The significant effect of HAMSA on FCR justifies further investigation as this may improve production efficiency in the post-weaning period following an enteric F4-ETEC infection.
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来源期刊
Journal of animal science
Journal of animal science 农林科学-奶制品与动物科学
CiteScore
4.80
自引率
12.10%
发文量
1589
审稿时长
3 months
期刊介绍: The Journal of Animal Science (JAS) is the premier journal for animal science and serves as the leading source of new knowledge and perspective in this area. JAS publishes more than 500 fully reviewed research articles, invited reviews, technical notes, and letters to the editor each year. Articles published in JAS encompass a broad range of research topics in animal production and fundamental aspects of genetics, nutrition, physiology, and preparation and utilization of animal products. Articles typically report research with beef cattle, companion animals, goats, horses, pigs, and sheep; however, studies involving other farm animals, aquatic and wildlife species, and laboratory animal species that address fundamental questions related to livestock and companion animal biology will be considered for publication.
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