{"title":"68Ga FAPI PET在肾移植患者弥散性诺卡菌病中的应用——一种有价值的感染成像方式。","authors":"Srinivas Ananth Kumar, Karthikeyan Subramanian, Bhagwant Rai Mittal, Harmandeep Singh, Rajender Kumar, Sarbpreet Singh","doi":"10.1007/s13139-024-00897-8","DOIUrl":null,"url":null,"abstract":"<p><p>Nocardiosis, an opportunistic infection occurs in immunodeficient population commonly in organ transplant recipients. Patients with risk factors likely chronic corticosteroids and immunosuppressants consumption usually have a higher tendency for disseminated infections with formation of deep abscesses at various sites in the body. Functional imaging with PET, being a whole body imaging offers information about the various sites of disease, thereby assisting the treatment planning, treatment response and also to identify the sites of biopsy. 68Ga FAPI PET serves this purpose as previous studies in various other infections have shown activated fibroblasts with increased FAP expression at the infective foci.</p>","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":"59 3","pages":"209-211"},"PeriodicalIF":2.7000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084474/pdf/","citationCount":"0","resultStr":"{\"title\":\"<sup>68</sup>Ga FAPI PET in a Renal Transplant Patient with Disseminated Nocardiosis-A Worthwhile Imaging Modality for Infection Imaging.\",\"authors\":\"Srinivas Ananth Kumar, Karthikeyan Subramanian, Bhagwant Rai Mittal, Harmandeep Singh, Rajender Kumar, Sarbpreet Singh\",\"doi\":\"10.1007/s13139-024-00897-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Nocardiosis, an opportunistic infection occurs in immunodeficient population commonly in organ transplant recipients. Patients with risk factors likely chronic corticosteroids and immunosuppressants consumption usually have a higher tendency for disseminated infections with formation of deep abscesses at various sites in the body. Functional imaging with PET, being a whole body imaging offers information about the various sites of disease, thereby assisting the treatment planning, treatment response and also to identify the sites of biopsy. 68Ga FAPI PET serves this purpose as previous studies in various other infections have shown activated fibroblasts with increased FAP expression at the infective foci.</p>\",\"PeriodicalId\":19384,\"journal\":{\"name\":\"Nuclear Medicine and Molecular Imaging\",\"volume\":\"59 3\",\"pages\":\"209-211\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084474/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nuclear Medicine and Molecular Imaging\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s13139-024-00897-8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/12/29 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nuclear Medicine and Molecular Imaging","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s13139-024-00897-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/29 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
68Ga FAPI PET in a Renal Transplant Patient with Disseminated Nocardiosis-A Worthwhile Imaging Modality for Infection Imaging.
Nocardiosis, an opportunistic infection occurs in immunodeficient population commonly in organ transplant recipients. Patients with risk factors likely chronic corticosteroids and immunosuppressants consumption usually have a higher tendency for disseminated infections with formation of deep abscesses at various sites in the body. Functional imaging with PET, being a whole body imaging offers information about the various sites of disease, thereby assisting the treatment planning, treatment response and also to identify the sites of biopsy. 68Ga FAPI PET serves this purpose as previous studies in various other infections have shown activated fibroblasts with increased FAP expression at the infective foci.
期刊介绍:
Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor.
The Korean Society of Nuclear Medicine (KSNM)
KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.