儿童视神经鞘脑膜瘤：基于病例系列的诊断挑战。

IF 2.4 3区医学 Q2 HEMATOLOGY

Pediatric Blood & Cancer Pub Date : 2025-04-24 DOI:10.1002/pbc.31739

Deysha Ratnasingham, George Lawson, Harpreet Hyare, Sam Gurney, John Apps, Ian Reekie, Sucheta Vaidya, Carmen Soto, Kavitha Srivatsa, Jaroslaw Peregud-Pogorzelski, Andrzej Brodkiewicz, Owase Jeelani, Mette Jorgensen, Sarita Depani, Darren Hargrave, Elwira Szychot

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引用次数: 0

摘要

儿童和青少年视神经鞘脑膜瘤（ONSM）的诊断仍然具有挑战性，尽管高质量的影像学进展。我们在英国的四个三级儿科肿瘤中心确定了7名被诊断为ONSM的儿童。我们的病例系列强调了PET-DOTATATE扫描在活检被认为是高风险时协助诊断的价值。计算机断层扫描（CT）可能有助于显示脑膜瘤内的钙化，这是在20%-50%的ONSM病例中发生的相对特异性的发现。不幸的是，尽管有最佳的治疗方法，一些患者的视力下降是不可避免的。为了改善结果，建议及时咨询多学科团队。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series.

The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high-quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom. Our case series highlighted the value of PET-DOTATATE scans in assisting diagnosis when biopsy was considered high risk. Computed tomography (CT) scan may be useful for demonstrating calcification within the meningioma, a relatively specific finding occurring in 20%-50% of ONSM cases. Unfortunately, despite optimal treatment, vision loss is unavoidable in some patients. To improve outcomes, prompt consultation with a multidisciplinary team is recommended.

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来源期刊

Pediatric Blood & Cancer 医学-小儿科

CiteScore

4.90

自引率

9.40%

发文量

546

审稿时长

1.5 months

期刊介绍： Pediatric Blood & Cancer publishes the highest quality manuscripts describing basic and clinical investigations of blood disorders and malignant diseases of childhood including diagnosis, treatment, epidemiology, etiology, biology, and molecular and clinical genetics of these diseases as they affect children, adolescents, and young adults. Pediatric Blood & Cancer will also include studies on such treatment options as hematopoietic stem cell transplantation, immunology, and gene therapy.