{"title":"药物性血小板减少症病因分析1例。","authors":"Vivian A Pham, Christopher Selby","doi":"10.6004/jadpro.2025.16.2.3","DOIUrl":null,"url":null,"abstract":"<p><p>Thrombocytopenia can be caused by various etiologies, one of which is immune-mediated destruction. Within the realm of immune thrombocytopenia, there can be multiple pathways and mechanisms that lead to platelet destruction. Finding the exact mechanism can be a crucial diagnostic step in deciding the most appropriate treatment of the platelet loss and in the therapeutic planning of a patient's comorbidities, especially in patients with malignancies. In this case report, we describe a patient with metastatic clear cell renal cell carcinoma who developed acute thrombocytopenia while preparing to initiate therapy for his malignancy.</p>","PeriodicalId":94110,"journal":{"name":"Journal of the advanced practitioner in oncology","volume":"16 2","pages":"65-71"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981883/pdf/","citationCount":"0","resultStr":"{\"title\":\"Digging into the Cause of Drug-Induced Thrombocytopenia: A Case Report.\",\"authors\":\"Vivian A Pham, Christopher Selby\",\"doi\":\"10.6004/jadpro.2025.16.2.3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Thrombocytopenia can be caused by various etiologies, one of which is immune-mediated destruction. Within the realm of immune thrombocytopenia, there can be multiple pathways and mechanisms that lead to platelet destruction. Finding the exact mechanism can be a crucial diagnostic step in deciding the most appropriate treatment of the platelet loss and in the therapeutic planning of a patient's comorbidities, especially in patients with malignancies. In this case report, we describe a patient with metastatic clear cell renal cell carcinoma who developed acute thrombocytopenia while preparing to initiate therapy for his malignancy.</p>\",\"PeriodicalId\":94110,\"journal\":{\"name\":\"Journal of the advanced practitioner in oncology\",\"volume\":\"16 2\",\"pages\":\"65-71\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981883/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the advanced practitioner in oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6004/jadpro.2025.16.2.3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the advanced practitioner in oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6004/jadpro.2025.16.2.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Digging into the Cause of Drug-Induced Thrombocytopenia: A Case Report.
Thrombocytopenia can be caused by various etiologies, one of which is immune-mediated destruction. Within the realm of immune thrombocytopenia, there can be multiple pathways and mechanisms that lead to platelet destruction. Finding the exact mechanism can be a crucial diagnostic step in deciding the most appropriate treatment of the platelet loss and in the therapeutic planning of a patient's comorbidities, especially in patients with malignancies. In this case report, we describe a patient with metastatic clear cell renal cell carcinoma who developed acute thrombocytopenia while preparing to initiate therapy for his malignancy.