一锅法合成苯并恶唑:一种制备芳香族杂环化合物的新方法。

IF 1.9 4区 医学 Q3 CHEMISTRY, MEDICINAL
Monika Chauhan, Sumitra Nain
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引用次数: 0

摘要

考虑到广泛合成操作的必要性,将各种反应整合到一个单一的锅操作中是提高合成效率的一个有趣的方法。一锅法可以最大限度地减少化学废物的产生,节省时间,避免多次净化过程,完成多次转化,在一锅中形成多个键。因此,在设计合成工艺时应考虑“锅经济”,因为一锅反应既有效又环保。杰出的合成在过去十年中迅速增加。本研究的主要目的是说明各种一锅法,导致有利的合成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
One-Pot Synthesis of Benzoxazoles: A Promising Approach to Aromatic Heterocyclic Compounds Preparation.

Considering the necessity for broad synthetic operations, integrating various reactions into a single pot operation is an intriguing approach to improve synthetic efficiency. One-pot operations may serve as an effective way to minimize the amount of chemical waste generated, save time, avoid multiple purification processes, accomplish numerous transformations, and make multiple bonds in one pot. Therefore, "pot economy" should be considered while designing a synthesis process, since a one-pot reaction can be effective and environmentally safe. Outstanding synthesis has rapidly increased over the last ten years. This study's main goal was to illustrate various one-pot methods that lead to advantageous synthesis.

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来源期刊
Medicinal Chemistry
Medicinal Chemistry 医学-医药化学
CiteScore
4.30
自引率
4.30%
发文量
109
审稿时长
12 months
期刊介绍: Aims & Scope Medicinal Chemistry a peer-reviewed journal, aims to cover all the latest outstanding developments in medicinal chemistry and rational drug design. The journal publishes original research, mini-review articles and guest edited thematic issues covering recent research and developments in the field. Articles are published rapidly by taking full advantage of Internet technology for both the submission and peer review of manuscripts. Medicinal Chemistry is an essential journal for all involved in drug design and discovery.
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