{"title":"[天然淋巴细胞白血病小鼠超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶活性研究]。","authors":"J A Madej, C Kaszubkiewicz, G Radzanowska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In the mice of the high leukemic strain, sick with natural lymphatic leukemia, the following parameters were determined on the 0 day, after 90, 180 and 270 days of observation: activity of the superoxide dismutase (SOD-EC1.15.1.1), glutathione peroxidase (GSH-px-EC1.11.1.9) in the blood and catalase activity in erythrocytes. It was observed that the activity of all three enzymes during the development of the leukemic process decreased. This phenomenon indicates the disturbance of the protective role of these enzymes against free radicals in leucogenesis in mice.</p>","PeriodicalId":20364,"journal":{"name":"Polskie archiwum weterynaryjne","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Superoxide dismutase, catalase and glutathione peroxidase activities in mice with natural lymphocytic leukemia].\",\"authors\":\"J A Madej, C Kaszubkiewicz, G Radzanowska\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In the mice of the high leukemic strain, sick with natural lymphatic leukemia, the following parameters were determined on the 0 day, after 90, 180 and 270 days of observation: activity of the superoxide dismutase (SOD-EC1.15.1.1), glutathione peroxidase (GSH-px-EC1.11.1.9) in the blood and catalase activity in erythrocytes. It was observed that the activity of all three enzymes during the development of the leukemic process decreased. This phenomenon indicates the disturbance of the protective role of these enzymes against free radicals in leucogenesis in mice.</p>\",\"PeriodicalId\":20364,\"journal\":{\"name\":\"Polskie archiwum weterynaryjne\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polskie archiwum weterynaryjne\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polskie archiwum weterynaryjne","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Superoxide dismutase, catalase and glutathione peroxidase activities in mice with natural lymphocytic leukemia].
In the mice of the high leukemic strain, sick with natural lymphatic leukemia, the following parameters were determined on the 0 day, after 90, 180 and 270 days of observation: activity of the superoxide dismutase (SOD-EC1.15.1.1), glutathione peroxidase (GSH-px-EC1.11.1.9) in the blood and catalase activity in erythrocytes. It was observed that the activity of all three enzymes during the development of the leukemic process decreased. This phenomenon indicates the disturbance of the protective role of these enzymes against free radicals in leucogenesis in mice.
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