对免疫系统激活感到焦虑

IF 34.7 1区医学 Q1 Neuroscience

Nature Reviews Neuroscience Pub Date : 2025-05-07 DOI:10.1038/s41583-025-00928-z

Sian Lewis

引用次数: 0

摘要

在免疫系统疾病如牛皮癣患者中，情绪障碍发生率增加的可能机制是，在小鼠中，升高的血清细胞因子IL-17A和IL-17C通过激活前基底外侧杏仁核中的神经元诱导焦虑样症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Getting anxious about immune system activation

A possible mechanism for the increased incidence of mood disorders in people with immune system disorders such as psoriasis is revealed where, in mice, elevated serum levels of the cytokines IL-17A and IL-17C induce anxiety-like symptoms via activation of neurons in the anterior basolateral amygdala.

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来源期刊

Nature Reviews Neuroscience 医学-神经科学

CiteScore

35.00

自引率

0.60%

发文量

104

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Neuroscience is a journal that is part of the Nature Reviews portfolio. It focuses on the multidisciplinary science of neuroscience, which aims to provide a complete understanding of the structure and function of the central nervous system. Advances in molecular, developmental, and cognitive neuroscience have made it possible to tackle longstanding neurobiological questions. However, the wealth of knowledge generated by these advancements has created a need for new tools to organize and communicate this information efficiently. Nature Reviews Neuroscience aims to fulfill this need by offering an authoritative, accessible, topical, and engaging resource for scientists interested in all aspects of neuroscience. The journal covers subjects such as cellular and molecular neuroscience, development of the nervous system, sensory and motor systems, behavior, regulatory systems, higher cognition and language, computational neuroscience, and disorders of the brain. Editorial decisions for the journal are made by a team of full-time professional editors who are PhD-level scientists.