儿童水肿性营养不良调节性糖尿病:一种罕见的疾病,不寻常的表现和治疗-个案报告

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Alemu Bogale, Tamirat Toma
{"title":"儿童水肿性营养不良调节性糖尿病:一种罕见的疾病,不寻常的表现和治疗-个案报告","authors":"Alemu Bogale,&nbsp;Tamirat Toma","doi":"10.1002/ccr3.70389","DOIUrl":null,"url":null,"abstract":"<p>The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70389","citationCount":"0","resultStr":"{\"title\":\"A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report\",\"authors\":\"Alemu Bogale,&nbsp;Tamirat Toma\",\"doi\":\"10.1002/ccr3.70389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 5\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-05-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70389\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70389\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

摘要

“营养不良双重负担”是指同一人群在一生中同时出现营养不足和营养过剩。慢性营养不良和肥胖都与糖尿病有关;前者在发展中国家更为普遍,可导致营养不良调节性糖尿病(MMDM)。本个案研究旨在教育发展中国家和欠发达国家的医生如何治疗糖尿病和营养不良。我们遇到了一个10岁的女孩,表现出水肿性营养不良和酮抵抗性糖尿病的体征和症状。住院45天后出院,大剂量胰岛素2.8 IU/kg/天,同时进行方75营养不良康复治疗。最后,我们提出并得出结论,有效的基于需求的胰岛素管理,以及基于世卫组织营养不良和糖尿病饮食指南的每日能量需求的营养康复对MMDM至关重要。在我们的案例中,随着时间的推移,营养康复带来的体重增加对她所需的胰岛素量没有影响,这违背了目前的知识,需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report

A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report

The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Clinical Case Reports
Clinical Case Reports MEDICINE, GENERAL & INTERNAL-
自引率
14.30%
发文量
1268
审稿时长
13 weeks
期刊介绍: Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信