{"title":"儿童水肿性营养不良调节性糖尿病:一种罕见的疾病,不寻常的表现和治疗-个案报告","authors":"Alemu Bogale, Tamirat Toma","doi":"10.1002/ccr3.70389","DOIUrl":null,"url":null,"abstract":"<p>The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70389","citationCount":"0","resultStr":"{\"title\":\"A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report\",\"authors\":\"Alemu Bogale, Tamirat Toma\",\"doi\":\"10.1002/ccr3.70389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 5\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-05-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70389\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70389\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report
The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).