丘脑切开术治疗局灶性手肌张力障碍的疗效和安全性:一项系统综述

IF 2.9 3区 医学 Q2 CLINICAL NEUROLOGY
Ruiqing Yang, Botao Xiong, Xiaoman Shi, Xinyuejia Huang, Wei Wang
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引用次数: 0

摘要

背景:局灶性手肌张力障碍(FHD)对手部运动功能有显著影响,尤其是对作家和音乐家。最近,许多神经外科医生使用丘脑切开术治疗难治性FHD;本系统综述旨在评估丘脑切开术治疗FHD的有效性和安全性。方法:检索PubMed、Medline和Embase,选取丘脑切开术治疗FHD的相关研究。提取人口学特征、手术参数、疗效和安全性。结果:对15项研究中的254例患者进行了系统评价。采用作者痉挛评定量表(WCRS)、写作运动评分(WMS)和症状严重程度评分(SSS)评定手肌张力障碍。此外,还评估了Tubiana音乐家的手肌张力障碍量表(TMDS)和特定任务局灶性手肌张力障碍量表(TSFD)的手部运动表现。48例(18.9%)出现短暂性并发症,9例(3.5%)出现永久性并发症。结论:丘脑切开术是治疗FHD的另一种选择。丘脑切开术可减轻手部肌张力障碍,改善手部运动功能。虽然丘脑切开术有一定的并发症,但永久性并发症的发生率相对较低。丘脑切开术术前需要充分评估以确保安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Efficacy and Safety of Thalamotomy for Focal Hand Dystonia: A Systematic Review

Efficacy and Safety of Thalamotomy for Focal Hand Dystonia: A Systematic Review

Background: Focal hand dystonia (FHD) has a significant impact on the hand motor function, especially for writers and musicians. Recently, many neurosurgeons have used thalamotomy to treat refractory FHD; this systematic review is aimed at assessing the efficacy and safety of thalamotomy for FHD.

Methods: PubMed, Medline, and Embase were searched to select relevant studies concerning thalamotomy for FHD. Demographic characteristics, surgical parameters, efficacy, and safety were extracted.

Results:A systematic review was performed including 254 patients among 15 studies. The writer’s cramp rating scale (WCRS), writing movement scores (WMS), and symptom severity scores (SSS) were assessed for hand dystonia disability. Besides, Tubiana musician’s dystonia scale (TMDS) and task-specific focal hand dystonia’s scale (TSFD) were assessed for hand motor performance. Transient complications were reported in 48 patients (18.9%) with permanent complications occurring in nine cases (3.5%).

Conclusion: Thalamotomy is an alternative option for FHD. Thalamotomy can alleviate hand dystonia disability and improve hand motor function. Although thalamotomy has certain complications, the incidence of permanent complications is relatively low. Thalamotomy needs to be fully evaluated before surgery to ensure safety.

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来源期刊
Acta Neurologica Scandinavica
Acta Neurologica Scandinavica 医学-临床神经学
CiteScore
6.70
自引率
2.90%
发文量
161
审稿时长
4-8 weeks
期刊介绍: Acta Neurologica Scandinavica aims to publish manuscripts of a high scientific quality representing original clinical, diagnostic or experimental work in neuroscience. The journal''s scope is to act as an international forum for the dissemination of information advancing the science or practice of this subject area. Papers in English will be welcomed, especially those which bring new knowledge and observations from the application of therapies or techniques in the combating of a broad spectrum of neurological disease and neurodegenerative disorders. Relevant articles on the basic neurosciences will be published where they extend present understanding of such disorders. Priority will be given to review of topical subjects. Papers requiring rapid publication because of their significance and timeliness will be included as ''Clinical commentaries'' not exceeding two printed pages, as will ''Clinical commentaries'' of sufficient general interest. Debate within the speciality is encouraged in the form of ''Letters to the editor''. All submitted manuscripts falling within the overall scope of the journal will be assessed by suitably qualified referees.
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