Ruiqing Yang, Botao Xiong, Xiaoman Shi, Xinyuejia Huang, Wei Wang
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Efficacy and Safety of Thalamotomy for Focal Hand Dystonia: A Systematic Review
Background: Focal hand dystonia (FHD) has a significant impact on the hand motor function, especially for writers and musicians. Recently, many neurosurgeons have used thalamotomy to treat refractory FHD; this systematic review is aimed at assessing the efficacy and safety of thalamotomy for FHD.
Methods: PubMed, Medline, and Embase were searched to select relevant studies concerning thalamotomy for FHD. Demographic characteristics, surgical parameters, efficacy, and safety were extracted.
Results:A systematic review was performed including 254 patients among 15 studies. The writer’s cramp rating scale (WCRS), writing movement scores (WMS), and symptom severity scores (SSS) were assessed for hand dystonia disability. Besides, Tubiana musician’s dystonia scale (TMDS) and task-specific focal hand dystonia’s scale (TSFD) were assessed for hand motor performance. Transient complications were reported in 48 patients (18.9%) with permanent complications occurring in nine cases (3.5%).
Conclusion: Thalamotomy is an alternative option for FHD. Thalamotomy can alleviate hand dystonia disability and improve hand motor function. Although thalamotomy has certain complications, the incidence of permanent complications is relatively low. Thalamotomy needs to be fully evaluated before surgery to ensure safety.
期刊介绍:
Acta Neurologica Scandinavica aims to publish manuscripts of a high scientific quality representing original clinical, diagnostic or experimental work in neuroscience. The journal''s scope is to act as an international forum for the dissemination of information advancing the science or practice of this subject area. Papers in English will be welcomed, especially those which bring new knowledge and observations from the application of therapies or techniques in the combating of a broad spectrum of neurological disease and neurodegenerative disorders. Relevant articles on the basic neurosciences will be published where they extend present understanding of such disorders. Priority will be given to review of topical subjects. Papers requiring rapid publication because of their significance and timeliness will be included as ''Clinical commentaries'' not exceeding two printed pages, as will ''Clinical commentaries'' of sufficient general interest. Debate within the speciality is encouraged in the form of ''Letters to the editor''. All submitted manuscripts falling within the overall scope of the journal will be assessed by suitably qualified referees.