钚-238 α粒子诱导G0淋巴细胞姐妹染色单体交换(SCE)。

International journal of radiation biology and related studies in physics, chemistry, and medicine Pub Date : 1988-06-01 DOI:10.1080/09553008814551271

S Z Aghamohammadi, D T Goodhead, J R Savage

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引用次数: 67

摘要

用钚-238 α粒子和x射线照射人G0淋巴细胞，研究姐妹染色单体交换(SCE)的产生。α -颗粒使SCE显著升高，当分离淋巴细胞辐照时，这种升高更为显著。x射线照射未引起SCE显著增加。因此，该系统中α粒子诱导SCE的相对生物有效性(RBE)是不确定的，实际上是无限的。

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Induction of sister chromatid exchanges (SCE) in G0 lymphocytes by plutonium-238 alpha-particles.

Irradiation of human G0 lymphocytes with plutonium-238 alpha-particles and X-rays was performed to investigate the production of sister chromatid exchanges (SCE). Alpha-particles produce a significant increase in SCE and this elevation is more significant when separated lymphocytes are irradiated. X-ray irradiation did not induce any significant increase in SCE. Therefore the relative biological effectiveness (RBE) for the induction of SCE by alpha-particles in this system is undefined and effectively infinite.

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International journal of radiation biology and related studies in physics, chemistry, and medicine

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