心智胜过微生物群：神经元在肠道中发号施令

IF 18.9 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2025-04-22 DOI:10.1038/s42255-025-01282-1

Wuling Zhong, Karen Wang, Amir Zarrinpar

引用次数: 0

摘要

尽管肠道微生物群可以影响大脑功能，但大脑活动驱动的微生物群落变化的证据有限。在这里，作者通过证明下丘脑回路的调节可以快速改变肠道微生物群组成，为脑-肠轴的双向通信提供了直接支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Mind over microbiota: neurons call the shots in the gut

查看原文本刊更多论文

Mind over microbiota: neurons call the shots in the gut

Although the gut microbiota can influence brain function, evidence for brain activity-driven changes in microbial communities is limited. Here, the authors provide direct support for bidirectional communication in the brain-to-gut axis by demonstrating that modulation of hypothalamic circuits can rapidly alter gut microbiota composition.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.