鼻咽癌放疗患者症状评估量表的研制与验证

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing Pub Date : 2025-03-21 DOI:10.1016/j.apjon.2025.100690

Fangying Wang , Qingyu Zhao , Guanmian Liang , Wanying Wu

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引用次数: 0

摘要

目的基于症状体验模型，编制鼻咽癌放疗患者症状评估量表（SAS-NPC）。方法在第一阶段，通过文献内容分析和小组讨论，构建了包含61个条目的初始库。经过16位专家的专家评审和对10位患者的认知访谈后，该库被精炼为56个项目。第二阶段采用方便抽样法，招募625例鼻咽癌放疗患者，对量表项目进行评估和探讨。第三阶段主要评估量表的信度和效度。结果SAS-NPC量表由7个维度33个项目组成。信度分析显示，总量表的Cronbach’s α系数为0.928，分半信度为0.790，重测信度为0.828。效度分析显示，量表各条目的内容效度指数在0.833 ~ 1.000之间，总体内容效度指数为0.970。探索性因子分析（EFA）确定了7个共同因素，占总方差的74.505%。验证性因子分析（CFA）显示良好的整体模型拟合。结论SAS-NPC全面捕捉鼻咽癌放疗患者的急性和长期症状。该量表具有较强的信度和效度，是评估鼻咽癌症状负担、方便临床症状管理的理想工具。

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Development and validation of the symptom assessment scale for patients with nasopharyngeal cancer undergoing radiotherapy

Objective

This study aims to develop the Symptom Assessment Scale for Patients with Nasopharyngeal Cancer Undergoing Radiotherapy (SAS-NPC), based on the Symptom Experience Model.

Methods

In Phase 1, a content analysis of the literature and group discussions were conducted to construct an initial pool of 61 items. Following expert review by 16 specialists and cognitive interviews with 10 patients, the pool was refined to 56 items. In Phase 2, a convenience sampling method was used to recruit 625 patients with nasopharyngeal cancer (NPC) undergoing radiotherapy, who assessed and explored the scale items. Phase 3 focused on evaluating the scale's reliability and validity.

Results

The SAS-NPC consists of 7 dimensions and 33 items. Reliability analysis revealed a Cronbach's α coefficient of 0.928 for the total scale, a split-half reliability of 0.790, and a retest reliability of 0.828. Validity analysis showed content validity indices for each item ranging from 0.833 to 1.000, with an overall content validity index of 0.970 for the scale. Exploratory factor analysis (EFA) identified 7 common factors, which accounted for 74.505% of the total variance. Confirmatory factor analysis (CFA) demonstrated good overall model fit.

Conclusions

The SAS-NPC comprehensively captures acute and long-term symptoms associated with patients with NPC undergoing radiotherapy. The scale exhibits strong reliability and validity, making it an ideal tool for assessing NPC symptom burden and facilitating clinical symptom management.

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