口服微藻生物系统增强不可逆电穿孔免疫治疗肝癌（Adv. Sci. 15/2025）

IF 14.3 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-04-17 DOI:10.1002/advs.202570101

Cheng Zeng, Shiyuan Hua, Jiayu Zhou, Tangye Zeng, Jianke Chen, Lijian Su, Angfeng Jiang, Min Zhou, Zhe Tang

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引用次数: 0

摘要

不可逆电穿孔免疫治疗在文章编号2409381中，周敏、唐哲等人介绍了一种基于微藻的给药系统，展示了携带免疫调节剂的工程微藻口服给药治疗肝癌。与不可逆电穿孔技术协同作用，激活全身抗肿瘤免疫。通过生物材料与物理治疗的创新合作，突破了传统治疗方法的局限性，为肝癌的精准免疫治疗提供了新的范例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Oral Microalgae-Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma (Adv. Sci. 15/2025)

查看原文本刊更多论文

Oral Microalgae-Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma (Adv. Sci. 15/2025)

Irreversible Electroporation Immunotherapy

In article number 2409381, Min Zhou, Zhe Tang, and co-workers present a microalgae-based drug delivery system, showcasing the oral administration of engineered microalgae carrying immunomodulators for liver cancer treatment. In synergy with irreversible electroporation technology, it activates systemic anti-tumor immunity. Through innovative collaboration between biomaterials and physiotherapy, it breaks through the limitations of traditional treatments and provides a new paradigm for precise immunotherapy of liver cancer.

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.