不宁腿综合征和老年痴呆患者的铁蛋白水平:一项横断面研究。

Q3 Medicine
Dementia e Neuropsychologia Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI:10.1590/1980-5764-DN-2024-0218
Érica Dayanne Meireles Leite, Madson Alan Maximiano-Barreto, Letícia Lambert, Victor Oliveira Wercelens, Álan Luiz Éckeli, Marcos Hortes Nisihara Chagas
{"title":"不宁腿综合征和老年痴呆患者的铁蛋白水平:一项横断面研究。","authors":"Érica Dayanne Meireles Leite, Madson Alan Maximiano-Barreto, Letícia Lambert, Victor Oliveira Wercelens, Álan Luiz Éckeli, Marcos Hortes Nisihara Chagas","doi":"10.1590/1980-5764-DN-2024-0218","DOIUrl":null,"url":null,"abstract":"<p><p>In cases of dementia or major neurocognitive disorder, restless legs syndrome has not been extensively studied because the diagnosis relies on clinical assessments and self-reports from patients.</p><p><strong>Objective: </strong>The aim of this study was to investigate the association between Willis-Ekbom disease/restless legs syndrome and iron-deficiency anemia in older adults with dementia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 70 older adults diagnosed with dementia and restless legs syndrome at a psychogeriatric clinic in the state of São Paulo, Brazil. The participants answered data collection instruments addressing sociodemographic characteristics, restless legs syndrome, neuropsychiatric symptoms, sleep quality, daytime sleepiness, and cognitive function. Creatinine, ferritin, red blood cells, hemoglobin, and hematocrit were determined by blood exams (the latter of which was collected from the patient records).</p><p><strong>Results: </strong>The sample was composed predominantly of individuals with mixed dementia (i.e., Alzheimer's disease+vascular dementia). Women accounted for 55.7% of the sample, with a mean age of 77.80±9.36 years. The prevalence of restless legs syndrome among the participants was found to be 15.7%. Individuals with this syndrome had greater frequencies of neuropsychiatric symptoms, poor sleep quality, higher BMI, and lower ferritin levels (p<0.05).</p><p><strong>Conclusion: </strong>The prevalence of restless legs syndrome among older adults with dementia was 15.7%, and individuals with this syndrome had ferritin deficiency.</p>","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"19 ","pages":"e20240218"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975294/pdf/","citationCount":"0","resultStr":"{\"title\":\"Restless legs syndrome and ferritin levels in older adults with dementia: a cross-sectional study.\",\"authors\":\"Érica Dayanne Meireles Leite, Madson Alan Maximiano-Barreto, Letícia Lambert, Victor Oliveira Wercelens, Álan Luiz Éckeli, Marcos Hortes Nisihara Chagas\",\"doi\":\"10.1590/1980-5764-DN-2024-0218\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In cases of dementia or major neurocognitive disorder, restless legs syndrome has not been extensively studied because the diagnosis relies on clinical assessments and self-reports from patients.</p><p><strong>Objective: </strong>The aim of this study was to investigate the association between Willis-Ekbom disease/restless legs syndrome and iron-deficiency anemia in older adults with dementia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 70 older adults diagnosed with dementia and restless legs syndrome at a psychogeriatric clinic in the state of São Paulo, Brazil. The participants answered data collection instruments addressing sociodemographic characteristics, restless legs syndrome, neuropsychiatric symptoms, sleep quality, daytime sleepiness, and cognitive function. Creatinine, ferritin, red blood cells, hemoglobin, and hematocrit were determined by blood exams (the latter of which was collected from the patient records).</p><p><strong>Results: </strong>The sample was composed predominantly of individuals with mixed dementia (i.e., Alzheimer's disease+vascular dementia). Women accounted for 55.7% of the sample, with a mean age of 77.80±9.36 years. The prevalence of restless legs syndrome among the participants was found to be 15.7%. Individuals with this syndrome had greater frequencies of neuropsychiatric symptoms, poor sleep quality, higher BMI, and lower ferritin levels (p<0.05).</p><p><strong>Conclusion: </strong>The prevalence of restless legs syndrome among older adults with dementia was 15.7%, and individuals with this syndrome had ferritin deficiency.</p>\",\"PeriodicalId\":39167,\"journal\":{\"name\":\"Dementia e Neuropsychologia\",\"volume\":\"19 \",\"pages\":\"e20240218\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975294/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dementia e Neuropsychologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1590/1980-5764-DN-2024-0218\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dementia e Neuropsychologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1980-5764-DN-2024-0218","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

在痴呆或严重神经认知障碍的病例中,不宁腿综合征尚未得到广泛研究,因为其诊断依赖于临床评估和患者的自我报告。目的:本研究旨在探讨Willis-Ekbom病/不宁腿综合征与老年痴呆患者缺铁性贫血之间的关系。方法:在巴西圣保罗州的一家老年精神科诊所,对70名被诊断患有痴呆和不宁腿综合征的老年人进行了一项横断面研究。参与者回答了关于社会人口学特征、不宁腿综合征、神经精神症状、睡眠质量、白天嗜睡和认知功能的数据收集工具。肌酐、铁蛋白、红细胞、血红蛋白和红细胞压积通过血液检查确定(后者从患者记录中收集)。结果:样本主要由混合性痴呆患者组成(即阿尔茨海默病+血管性痴呆)。女性占55.7%,平均年龄77.80±9.36岁。不宁腿综合征在参与者中的患病率为15.7%。该综合征患者出现神经精神症状的频率更高,睡眠质量差,BMI较高,铁蛋白水平较低(结论:老年痴呆患者中不宁腿综合征的患病率为15.7%,该综合征患者存在铁蛋白缺乏症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Restless legs syndrome and ferritin levels in older adults with dementia: a cross-sectional study.

In cases of dementia or major neurocognitive disorder, restless legs syndrome has not been extensively studied because the diagnosis relies on clinical assessments and self-reports from patients.

Objective: The aim of this study was to investigate the association between Willis-Ekbom disease/restless legs syndrome and iron-deficiency anemia in older adults with dementia.

Methods: A cross-sectional study was conducted with 70 older adults diagnosed with dementia and restless legs syndrome at a psychogeriatric clinic in the state of São Paulo, Brazil. The participants answered data collection instruments addressing sociodemographic characteristics, restless legs syndrome, neuropsychiatric symptoms, sleep quality, daytime sleepiness, and cognitive function. Creatinine, ferritin, red blood cells, hemoglobin, and hematocrit were determined by blood exams (the latter of which was collected from the patient records).

Results: The sample was composed predominantly of individuals with mixed dementia (i.e., Alzheimer's disease+vascular dementia). Women accounted for 55.7% of the sample, with a mean age of 77.80±9.36 years. The prevalence of restless legs syndrome among the participants was found to be 15.7%. Individuals with this syndrome had greater frequencies of neuropsychiatric symptoms, poor sleep quality, higher BMI, and lower ferritin levels (p<0.05).

Conclusion: The prevalence of restless legs syndrome among older adults with dementia was 15.7%, and individuals with this syndrome had ferritin deficiency.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Dementia e Neuropsychologia
Dementia e Neuropsychologia Medicine-Geriatrics and Gerontology
CiteScore
2.20
自引率
0.00%
发文量
58
审稿时长
8 weeks
期刊介绍: Dementia top Neuropsychologia the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and of the Brazilian Association of Geriatric Neuropsychiatry, is published by the "Associação Neurologia Cognitiva e do Comportamento", a nonprofit Brazilian association. Regularly published on March, June, September, and December since 2007.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信