{"title":"吡喃熔合类似物及其潜在应用","authors":"Sumit Kumar, Aditi Arora, Sandeep Kumar, Rajesh Kumar, Nihar Nalini Senapati, Brajendra K. Singh","doi":"10.1134/S1068162024606001","DOIUrl":null,"url":null,"abstract":"<p>Heterocyclic compounds represent one of the most prominent classes of currently used pharmaceuticals. Among these, the pyran ring has attracted significant research interest due to its broad spectrum of pharmacological properties. Notably, molecules such as benzopyrans, chromones, flavonoids, coumarins, xanthones, and naphthoquinones—each featuring a pyran core—exhibit diverse biological activities. This structural motif is widely present in both naturally occurring and synthetically derived compounds. The remarkable medicinal properties of various natural products, including pyrans and benzopyrans, have captivated the scientific community. This report provides a concise overview of the synthesis, characterization, and therapeutic applications of pyran-fused analogues.</p>","PeriodicalId":758,"journal":{"name":"Russian Journal of Bioorganic Chemistry","volume":"51 2","pages":"373 - 438"},"PeriodicalIF":1.1000,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pyran-Fused Analogues and Their Potential Applications\",\"authors\":\"Sumit Kumar, Aditi Arora, Sandeep Kumar, Rajesh Kumar, Nihar Nalini Senapati, Brajendra K. Singh\",\"doi\":\"10.1134/S1068162024606001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Heterocyclic compounds represent one of the most prominent classes of currently used pharmaceuticals. Among these, the pyran ring has attracted significant research interest due to its broad spectrum of pharmacological properties. Notably, molecules such as benzopyrans, chromones, flavonoids, coumarins, xanthones, and naphthoquinones—each featuring a pyran core—exhibit diverse biological activities. This structural motif is widely present in both naturally occurring and synthetically derived compounds. The remarkable medicinal properties of various natural products, including pyrans and benzopyrans, have captivated the scientific community. This report provides a concise overview of the synthesis, characterization, and therapeutic applications of pyran-fused analogues.</p>\",\"PeriodicalId\":758,\"journal\":{\"name\":\"Russian Journal of Bioorganic Chemistry\",\"volume\":\"51 2\",\"pages\":\"373 - 438\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-04-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Bioorganic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1068162024606001\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Bioorganic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1068162024606001","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Pyran-Fused Analogues and Their Potential Applications
Heterocyclic compounds represent one of the most prominent classes of currently used pharmaceuticals. Among these, the pyran ring has attracted significant research interest due to its broad spectrum of pharmacological properties. Notably, molecules such as benzopyrans, chromones, flavonoids, coumarins, xanthones, and naphthoquinones—each featuring a pyran core—exhibit diverse biological activities. This structural motif is widely present in both naturally occurring and synthetically derived compounds. The remarkable medicinal properties of various natural products, including pyrans and benzopyrans, have captivated the scientific community. This report provides a concise overview of the synthesis, characterization, and therapeutic applications of pyran-fused analogues.
期刊介绍:
Russian Journal of Bioorganic Chemistry publishes reviews and original experimental and theoretical studies on the structure, function, structure–activity relationships, and synthesis of biopolymers, such as proteins, nucleic acids, polysaccharides, mixed biopolymers, and their complexes, and low-molecular-weight biologically active compounds (peptides, sugars, lipids, antibiotics, etc.). The journal also covers selected aspects of neuro- and immunochemistry, biotechnology, and ecology.