吡喃熔合类似物及其潜在应用

IF 1.1 4区 化学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Sumit Kumar, Aditi Arora, Sandeep Kumar, Rajesh Kumar, Nihar Nalini Senapati, Brajendra K. Singh
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引用次数: 0

摘要

杂环化合物是目前应用最广泛的一类药物。其中,吡喃环因其广泛的药理特性而引起了人们的极大兴趣。值得注意的是,苯并吡喃类、色酮类、类黄酮类、香豆素类、山酮类和萘醌类分子都以吡喃核为特征,表现出不同的生物活性。这种结构基序广泛存在于天然存在的和合成衍生的化合物中。包括吡喃类和苯并吡喃类在内的各种天然产物的显著药用特性吸引了科学界的注意。本报告提供了一个简明的概述,合成,表征,和吡喃融合类似物的治疗应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pyran-Fused Analogues and Their Potential Applications

Pyran-Fused Analogues and Their Potential Applications

Heterocyclic compounds represent one of the most prominent classes of currently used pharmaceuticals. Among these, the pyran ring has attracted significant research interest due to its broad spectrum of pharmacological properties. Notably, molecules such as benzopyrans, chromones, flavonoids, coumarins, xanthones, and naphthoquinones—each featuring a pyran core—exhibit diverse biological activities. This structural motif is widely present in both naturally occurring and synthetically derived compounds. The remarkable medicinal properties of various natural products, including pyrans and benzopyrans, have captivated the scientific community. This report provides a concise overview of the synthesis, characterization, and therapeutic applications of pyran-fused analogues.

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来源期刊
Russian Journal of Bioorganic Chemistry
Russian Journal of Bioorganic Chemistry 生物-生化与分子生物学
CiteScore
1.80
自引率
10.00%
发文量
118
审稿时长
3 months
期刊介绍: Russian Journal of Bioorganic Chemistry publishes reviews and original experimental and theoretical studies on the structure, function, structure–activity relationships, and synthesis of biopolymers, such as proteins, nucleic acids, polysaccharides, mixed biopolymers, and their complexes, and low-molecular-weight biologically active compounds (peptides, sugars, lipids, antibiotics, etc.). The journal also covers selected aspects of neuro- and immunochemistry, biotechnology, and ecology.
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