膀胱肾腺瘤。临床特征、长期随访和复发预测因素。

IF 1.3 Q3 UROLOGY & NEPHROLOGY
Arab Journal of Urology Pub Date : 2024-09-11 eCollection Date: 2025-01-01 DOI:10.1080/20905998.2024.2402585
Mohamed H Zahran, Mohamed Shehata, Shery Khater, Hosam Nabeeh, Mohamed Ali Badawy, Ahmed Mosbah, Hassan Abol-Enein
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引用次数: 0

摘要

目的:总结膀胱肾源性腺瘤(NA)的临床特点,探讨其长期复发率。材料与方法:回顾性分析2000 ~ 2023年间所有诊断为膀胱NA的病例。回顾所有患者的人口统计学、症状、既往膀胱手术史、NA的宏观和微观特征以及巧合病理。评估长期复发率,包括恶性复发率。对复发预测因子进行单因素和多因素分析。结果:我们确定了24例诊断为NA的患者,平均(SD,范围)年龄为56岁(16,15 -73)岁。18例(75%)患者既往有膀胱手术史。膀胱镜下的宏观外观分别为8例、7例、5例和4例,分别为息肉状、扁平天鹅绒状、乳头状和结节状。在35个月(18-145个月)的中位(范围)随访中,15例(63%)患者分别在9例、3例和3例中出现了一次复发,包括NA、非特异性膀胱炎和尿路上皮癌(UC)。其中5人有第二次复发,1人有第三次复发。恶性复发患者既往有UC病史,其中2例需要根治性膀胱切除术和尿路转移。既往TURBT是复发的唯一独立预测因子[OR (95% CI) = 28 (2-37), p = 0.01]。结论:肾源性腺瘤是一种临床上类似恶性病变的良性疾病。它与高复发率有关。既往膀胱病变切除是复发的独立预测因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nephrogenic adenoma of the urinary bladder. Clinical features, long-term follow-up and recurrence predictors.

Objectives: To review the clinical features of nephrogenic adenoma (NA) of the urinary bladder and assess the long-term recurrence rates.

Material and methods: A retrospective analysis of all diagnosed NA of the urinary bladder between 2000 and 2023 was done. All patients' demographics, symptoms, history of previous bladder surgeries, macroscopic and microscopic features of NA and coincidental pathology were reviewed. The long-term recurrence rate including malignant recurrence was assessed. Univariate and multivariate analysis of predictor of recurrence was performed.

Results: We identified 24 patients diagnosed with NA with a mean (SD, range) age of 56 (16, 15-73) years. Eighteen (75%) patients had previous history of bladder surgeries. Macroscopic appearance on cystoscopy looked polypoidal, flat velvety, papillary and nodular in eight, seven, five, and four patients, respectively. At a median (range) follow-up of 35 (18-145) months, 15 (63%) patients developed one recurrence including NA, non-specific cystitis and urothelial carcinoma (UC) in nine, three and three patients, respectively. Of them, five had a second recurrence, and one patient had a third recurrence. Patients with malignant recurrence had previous history of UC and two of them required radical cystectomy and urinary diversion. Previous TURBT was the only independent predictor for recurrence [OR (95% CI) = 28 (2-37), p = 0.01].

Conclusion: Nephrogenic adenoma is a benign disease that mimics malignant lesion clinically. It is associated with high recurrence rate. Previous resection of bladder lesion is the independent predictor of the recurrence.

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来源期刊
Arab Journal of Urology
Arab Journal of Urology UROLOGY & NEPHROLOGY-
CiteScore
2.80
自引率
0.00%
发文量
40
期刊介绍: The Arab Journal of Urology is a peer-reviewed journal that strives to provide a high standard of research and clinical material to the widest possible urological community worldwide. The journal encompasses all aspects of urology including: urological oncology, urological reconstructive surgery, urodynamics, female urology, pediatric urology, endourology, transplantation, erectile dysfunction, and urinary infections and inflammations. The journal provides reviews, original articles, editorials, surgical techniques, cases reports and correspondence. Urologists, oncologists, pathologists, radiologists and scientists are invited to submit their contributions to make the Arab Journal of Urology a viable international forum for the practical, timely and state-of-the-art clinical urology and basic urological research.
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