Native group-directed double Heck arylation of internal alkenes via selective β-H elimination†

A Pd-catalyzed, ligand-free method for β,δ-selective consecutive arylation of internal alkenes with aryl iodides has been developed. This transformation employs a native group-directed double Heck arylation, utilizing selective β-H elimination to achieve precise regiochemical control. The protocol demonstrates high efficiency and broad functional group tolerance.