阻塞性睡眠呼吸暂停患者腹部内脏脂肪与喉咽反流的相关性

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-05-01 Epub Date: 2025-03-21 DOI:10.1007/s00405-025-09320-0

Xiangrong Cao, Yanru Duan, Yibo Hao, Zhe Wang, Chenhai Zheng, Zhiming Zhang, Jie Qin, Dahai Wu

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引用次数: 0

摘要

目的：探讨阻塞性睡眠呼吸暂停（OSA）患者腹部内脏脂肪与喉咽反流（LPR）的相关性。方法：本研究纳入72例OSA患者，根据体成分分析测量腹部内脏脂肪面积（VFA）并完成反流症状指数（RSI）评分后，分析腹部内脏脂肪与LPR严重程度的相关性。最后，为了进一步明确VFA对LPR的影响，对收集到的相关参数进行多元线性回归分析。结果：偏相关分析显示VFA与RSI评分呈正相关（r = 0.502, p）。结论：我们的研究发现VFA与OSA患者RSI评分相关，而BMI与RSI评分无独立相关性。这提示我们应该重视腹部内脏脂肪对OSA患者LPR的影响，未来还需要更多的实验来阐明两者之间的关系。

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Correlation between abdominal visceral fat and laryngopharyngeal reflux in patients with obstructive sleep apnea.

Purpose: To research the correlation between abdominal visceral fat and laryngopharyngeal reflux (LPR) in patients with obstructive sleep apnea (OSA).

Methods: This study included 72 OSA patients, and the correlation between abdominal visceral fat and the severity of LPR was analyzed after abdominal visceral fat area (VFA) was measured according to body composition analysis and reflux symptom index (RSI) score was completed. Finally, in order to further clarify the effect of VFA on LPR, multiple linear regression analysis was performed on the collected related parameters.

Results: Partial correlation analysis showed that the VFA was positively correlated with the RSI score (r = 0.502, p < 0.001) after controlling for apnea-hypopnea index (AHI), body mass index (BMI), lowest oxygen saturation (LSO₂), age, and sex. The multiple linear regression analysis indicated that VFA and AHI were the factors influencing LPR (t = 4.678, p < 0.001; t = 3.164, p = 0.002).

Conclusion: Our study found that VFA was associated with RSI score in OSA patients, but BMI didn't show an independent correlation with RSI score. This indicated that we should pay attention to the effect of abdominal visceral fat on LPR in OSA patients, and more experiments are needed in the future to clarify the relationship between the two.

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.