晚期前列腺癌治疗的最新研究亮点。

IF 2.8 4区 医学 Q2 ONCOLOGY
Current Opinion in Oncology Pub Date : 2025-05-01 Epub Date: 2025-03-19 DOI:10.1097/CCO.0000000000001128
Theodore Gourdin
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引用次数: 0

摘要

综述目的:本综述的目的是强调最近的研究集中在改善晚期前列腺癌患者的预后。最近的发现:最近的随机试验表明,使用新型激素药物和在某些情况下使用化疗治疗晚期前列腺癌的优势。转移性前列腺癌的最佳系统治疗序列仍有待确定,重点是生物标志物,这些生物标志物可能会选择需要新疗法的男性。一些患有少转移性疾病的男性可能从局部治疗中获益,研究继续关注于对这些男性的最佳选择。放射性药物正在改变晚期前列腺癌的治疗模式,正在努力通过更好的生物标志物和新的治疗组合来改善疗效。总结:正在进行的研究集中在改进现有治疗方法的使用和开发新的治疗方法和联合治疗晚期前列腺癌的男性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Highlights of recent research focused on the treatment of advanced prostate cancer.

Purpose of review: This review is designed to highlight recent research focused on improving outcomes in men with advanced prostate cancer.

Recent findings: Recent randomized trials have suggested advantages to treating men with advanced prostate cancer earlier in their disease course with novel hormonal agents and in some cases chemotherapy. Work remains to identify the optimal sequence of systemic therapies for metastatic prostate cancer with a focus on biomarkers that might select men in need of novel therapeutics. Some men with oligometastatic disease may benefit from localized therapy to sites of isolated progression and research continues to focus on optimally selecting these men. Radiopharmaceuticals are changing the treatment paradigm in advanced prostate cancer with efforts ongoing to improve outcomes with better biomarkers for response and novel treatment combinations.

Summary: Ongoing research focuses on refining the use of existing therapeutics and developing novel treatments and combinations for men with advanced prostate cancer.

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来源期刊
Current Opinion in Oncology
Current Opinion in Oncology 医学-肿瘤学
CiteScore
6.10
自引率
2.90%
发文量
130
审稿时长
4-8 weeks
期刊介绍: With its easy-to-digest reviews on important advances in world literature, Current Opinion in Oncology offers expert evaluation on a wide range of topics from sixteen key disciplines including sarcomas, cancer biology, melanoma and endocrine tumors. Published bimonthly, each issue covers in detail the most pertinent advances in these fields from the previous year. This is supplemented by annotated references detailing the merits of the most important papers.
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