少关节幼年特发性关节炎儿童关节B细胞的性别差异

IF 11.4 1区医学 Q1 RHEUMATOLOGY

Arthritis & Rheumatology Pub Date : 2025-03-17 DOI:10.1002/art.43157

Ki Pui Lam, Claudia Harris, Maria L Taylor, Daniela Fernandez-Salinas, Jing Cui, Biju Issac, Liang Sun, Indu Raman, Chengsong Zhu, Maryrose Hahn, Maryam Ashoor, Ahmad Bakhsh, Maria C Bryant, Siobhan Case, Mia Chandler, Joyce C Chang, Ezra Cohen, Fatma Dedeoglu, Olha Halyabar, Jonathan S Hausmann, Melissa Hazen, Daniel Ibanez, Liyoung Kim, Jeffrey Lo, Mindy S Lo, Esra Meidan, Megan Perron, Helene Powers, Mary Beth Son, Holly Wobma, Erin Janssen, Pui Y Lee, Peter A Nigrovic, Laurie Ohlms, A Eliot Shearer, Margaret H Chang, Maria Gutierrez-Arcelus, Lauren A Henderson

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引用次数: 0

摘要

T外周辅助细胞(Tph)-B细胞相互作用紊乱与多种形式的炎性关节炎有关，包括少关节幼年特发性关节炎（oligo JIA）。我们试图通过分析关节内B细胞来评估寡聚JIA的Tph-B细胞轴。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sex Differences in B Cells from the Joints of Children with Oligoarticular Juvenile Idiopathic Arthritis

Disordered T peripheral helper (Tph)-B cell interactions have been implicated in several forms of inflammatory arthritis, including oligoarticular juvenile idiopathic arthritis (oligo JIA). We sought to evaluate the Tph-B cell axis in oligo JIA through an analysis of intra-articular B cells.

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来源期刊

Arthritis & Rheumatology RHEUMATOLOGY-

CiteScore

20.90

自引率

3.00%

发文量

371

期刊介绍： Arthritis & Rheumatology is the official journal of the American College of Rheumatology and focuses on the natural history, pathophysiology, treatment, and outcome of rheumatic diseases. It is a peer-reviewed publication that aims to provide the highest quality basic and clinical research in this field. The journal covers a wide range of investigative areas and also includes review articles, editorials, and educational material for researchers and clinicians. Being recognized as a leading research journal in rheumatology, Arthritis & Rheumatology serves the global community of rheumatology investigators and clinicians.