一种用于芯片抗癌应用的注射成型改性硅橡胶。抛光工艺。6/2025)

IF 6.4 3区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Materials Technologies Pub Date : 2025-03-18 DOI:10.1002/admt.202570029

Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten

{"title":"一种用于芯片抗癌应用的注射成型改性硅橡胶。抛光工艺。6/2025)","authors":"Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten","doi":"10.1002/admt.202570029","DOIUrl":null,"url":null,"abstract":"<p><b>Cancer-on-Chip</b></p><p>In article number 2401450, Maayke M. P. Kuijten and co-workers present the culture of duo-layers with cancer cells on one and endothelial cells (to mimic a blood vessel) on the other. These cells have been cultured under continuous flow on an injection-molded functionalized PDMS fluidic insert for the Micronit® system and demonstrates the suitability of the inserts for building relevant cancer models on chip.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 6","pages":""},"PeriodicalIF":6.4000,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570029","citationCount":"0","resultStr":"{\"title\":\"An Injection-Molded Modified Silicone Rubber for Cancer-on-Chip Applications (Adv. Mater. Technol. 6/2025)\",\"authors\":\"Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten\",\"doi\":\"10.1002/admt.202570029\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Cancer-on-Chip</b></p><p>In article number 2401450, Maayke M. P. Kuijten and co-workers present the culture of duo-layers with cancer cells on one and endothelial cells (to mimic a blood vessel) on the other. These cells have been cultured under continuous flow on an injection-molded functionalized PDMS fluidic insert for the Micronit® system and demonstrates the suitability of the inserts for building relevant cancer models on chip.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":7292,\"journal\":{\"name\":\"Advanced Materials Technologies\",\"volume\":\"10 6\",\"pages\":\"\"},\"PeriodicalIF\":6.4000,\"publicationDate\":\"2025-03-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570029\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Materials Technologies\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/admt.202570029\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Materials Technologies","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/admt.202570029","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

在第2401450篇文章中，Maayke M. P. Kuijten和他的同事提出了一种双层细胞的培养方法，一层是癌细胞，另一层是内皮细胞（模拟血管）。这些细胞在microit®系统的注射成型功能化PDMS流体插入物上连续培养，并证明了插入物在芯片上构建相关癌症模型的适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

An Injection-Molded Modified Silicone Rubber for Cancer-on-Chip Applications (Adv. Mater. Technol. 6/2025)

查看原文本刊更多论文

An Injection-Molded Modified Silicone Rubber for Cancer-on-Chip Applications (Adv. Mater. Technol. 6/2025)

Cancer-on-Chip

In article number 2401450, Maayke M. P. Kuijten and co-workers present the culture of duo-layers with cancer cells on one and endothelial cells (to mimic a blood vessel) on the other. These cells have been cultured under continuous flow on an injection-molded functionalized PDMS fluidic insert for the Micronit® system and demonstrates the suitability of the inserts for building relevant cancer models on chip.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Advanced Materials Technologies Materials Science-General Materials Science

CiteScore

10.20

自引率

4.40%

发文量

566

期刊介绍： Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.