IF 1.5 Q2 MEDICINE, GENERAL & INTERNAL
Rasha S. Alradadi MBBS, MS , layan A. Aljohani MBBS , Rawan F. Alharbi MBBS , Ghadah T. Alsahli MBBS , Hiba Z. Barri MBBS , Rehab S. Alahmadi MBBS , Sami A. Al-Dubai MPH, PhD
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引用次数: 0

摘要

本研究旨在确定沙特阿拉伯王国(KSA) 1994年至2017年23年间儿童和青少年甲状腺癌(TC)的发病率。方法从沙特国家癌症登记处提取1994年至2017年诊断为TC的0-19岁个体的数据。回顾性分析TC发病率,沙特阿拉伯人口的年龄标准化,并根据性别、国籍(沙特和非沙特)和诊断年龄(0-4岁、5-9岁、10-14岁和15-19岁)每10万人表示TC发病率。由于信息不完整,排除了TC类型、肿瘤、淋巴结和转移分期的数据。结果706例患者在研究期间被诊断为TC,其中86.3%来自KSA。2012 - 2014年发病率最高(114例)。粗发病率(CIR) 1994-1996年最低(4.45/10万),15-16岁最高(26.7/10万)。女性受TC的影响尤为严重,平均CIR为45/10万,而男性为8.2/10万。从地理上看,利雅得的CIR最高,特别是在2004年(6.9/10万)、2016年(15.4/10万)和2017年(15.1/10万)。结论1994 - 2017年,KSA儿童青少年TC发病率增加了3倍,2012 - 2014年达到高峰。有必要进行进一步的研究,以调查导致这种增加趋势的因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trends of thyroid cancer in children and adolescents over 23 Years in KSA

Objective

This study aimed to determine the incidence of thyroid cancer (TC) in children and adolescents in the Kingdom of Saudi Arabia (KSA) during 23 years from 1994 to 2017.

Methods

Data were extracted from the Saudi National Cancer Registry for individuals aged 0–19 years diagnosed with TC from 1994 to 2017. TC incidence was retrospectively analyzed, age standardized for the Saudi Arabian population, and expressed per 100,000 people based on sex, nationality (Saudi and non-Saudi), and age at diagnosis (0–4, 5–9, 10–14, and 15–19 years). Data regarding the type of TC and tumor, node, and metastasis staging were excluded due to incomplete information.

Results

Overall, 706 patients were diagnosed with TC during the study period and 86.3 % were from KSA. The highest incidence (114) was observed between 2012 and 2014. The lowest crude incidence rate (CIR) was observed in 1994–1996 (4.45/100,000), and the CIR was highest among patients aged 15–16 years (26.7/100,000). Women were disproportionally affected by TC, with an average CIR of 45/100,000 compared with 8.2/100,000 in men. Geographically, Riyadh had the highest CIR, particularly in 2004 (6.9/100,000), 2016 (15.4/100,000), and 2017 (15.1/100,000).

Conclusion

A three-fold increase was observed in the incidence of TC among children and adolescents in KSA from 1994 to 2017, reaching a peak between 2012 and 2014. Further studies are warranted to investigate the factors that contributed to this increasing trend.
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来源期刊
Journal of Taibah University Medical Sciences
Journal of Taibah University Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
3.40
自引率
4.50%
发文量
130
审稿时长
29 days
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