非综合征患者恒牙缺失与其他牙齿畸形之间的关系：系统回顾

IF 2.2 4区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Archives of oral biology Pub Date : 2025-03-07 DOI:10.1016/j.archoralbio.2025.106223

Paula Cristiana Santos de Aguiar , Caio Melo Mesquita , Fabiana Evangelista Lerner , Laura Bezerra Borges , Rodrigo Rodrigues , Walbert A. Vieira , Luiz Renato Paranhos , Rui Barbosa de Brito Júnior

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引用次数: 0

摘要

背景：大多数牙齿发育不全的病例都表现为牙下畸形和不同类型的缺牙。此外，牙齿发育不全和其他异常在临床上也经常有关联。目的对非综合征患者恒牙发育不全合并其他牙畸形的文献进行系统分析。材料和方法在七个主要数据库（Embase、LILACS、BBO、MedLine via PubMed、SciELO、Scopus和Web of Science）和两个附加数据库（OATD和ProQuest）中进行电子检索，以部分捕获“灰色文献”。PECO策略用于鉴定观察性研究，评估非综合征患者中与其他牙齿异常相关的恒牙发育不全的患病率，不受发表语言或年份的限制。两名审稿人提取了数据，并使用JBI关键评估工具评估了符合条件的研究的个体偏倚风险，这些工具用于JBI系统评价-横断面、病例对照和队列研究清单。结果电子检索结果为8659份，其中7份符合入选条件，纳入定性综合。这些研究发表于1961年至2024年。发育不全的患者更容易出现牛牙症、小牙症、牙釉质发育不全和第二前磨牙脱角。在符合条件的研究中，异位萌出、第一乳牙下咬合和阻生牙的结果好坏参半。结论基于有限的证据，牙齿发育不全与其他并发牙齿发育不全的患病率呈正相关。

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Association between agenesis of permanent teeth and other dental anomalies in nonsyndromic patients: Systematic review

Background

Most cases of tooth agenesis are presented in the form of hypodontia with different patterns of missing teeth. In addition, there is a frequent clinical association between tooth agenesis and other anomalies.

Objective

To systematically analyze the literature on the prevalence of agenesis of permanent teeth associated with other dental anomalies in nonsyndromic patients.

Material and methods

An electronic search was performed in seven primary databases (Embase, LILACS, BBO, MedLine via PubMed, SciELO, Scopus, and Web of Science) and two additional ones (OATD, and ProQuest) to partially capture the "gray literature." The PECO strategy was used to identify observational studies evaluating the prevalence of agenesis of permanent teeth associated with other dental anomalies in nonsyndromic patients, without restrictions on publication language or year. Two reviewers extracted the data and assessed the individual risk of bias of the eligible studies using the JBI Critical Appraisal Tools for use in JBI Systematic Reviews - Checklist for Cross-sectional, Case-Control, and Cohort Studies.

Results

The electronic search revealed 8659 records, seven of which met the eligibility criteria, and were included in the qualitative synthesis. The studies were published from 1961 to 2024. Patients with agenesis were more likely to present taurodontism, microdontia, enamel hypoplasia and distoangulation of the second premolar. Ectopic eruption, infraocclusion of the first deciduous molar and impacted tooth showed mixed results among the eligible studies.

Conclusion

Based on limited evidence, tooth agenesis was positively associated with the prevalence of other concomitant tooth agenesis.

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来源期刊

Archives of oral biology 医学-牙科与口腔外科

CiteScore

5.10

自引率

3.30%

发文量

177

审稿时长

26 days

期刊介绍： Archives of Oral Biology is an international journal which aims to publish papers of the highest scientific quality in the oral and craniofacial sciences. The journal is particularly interested in research which advances knowledge in the mechanisms of craniofacial development and disease, including: Cell and molecular biology Molecular genetics Immunology Pathogenesis Cellular microbiology Embryology Syndromology Forensic dentistry