妇女心血管健康研究优先领域的国际视角：一项横断面调查的定性结果

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

CJC Open Pub Date : 2025-03-01 DOI:10.1016/j.cjco.2024.12.001

Stacey Matthews MPH , Christine Faubert PhD , Stephanie Couperthwaite BSc , Brian H. Rowe MD, MSc , Global Cardiovascular Research Funders Forum

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引用次数: 0

摘要

全球心血管研究资助者论坛（GCRFF）联合了对支持心血管疾病（CVD）研究感兴趣的国际研究资助者。一个重点领域是妇女的心血管健康；本研究旨在确定未来联合研究资助机会的优先主题。方法伦理批准后，根据文献综述、GCRFF反馈和方法学家/内容专家的意见进行调查。调查包括3个开放式问题和5个选择题。采用广泛传播的策略，从2023年11月15日至2024年1月15日，开启了为期8周的电子调查门户，提供多种语言选择。结果被下载到安全的REDCap数据库中进行分析。由3名审稿人完成独立的回答主题，直到达成编码共识，然后由1名编码员完成剩余的主题。报告了描述性统计数据。结果191个答复中，GCRFF的9个国家均有代表。大多数应答者被确定为女性（74%）和临床医生/学者（77%）；有生活或生活经验的人较少（23%）。共同的主题包括女性特有的风险因素和预防策略（56%）、生命过程问题（43%）以及针对性别和性别的治疗和结果（36%）。常见的主题是心血管疾病（66%）、冠状动脉疾病（CAD）（18%）和心脏病（13%）。指定的研究支柱包括临床（52%）、人口健康（36%）和基础科学（30%）。提出的解决方案包括知识生成（71%）、增加资金（55%）、网络研究人员（52%）和知识动员（41%）。性别与被调查者居住亚群之间的优先顺序一致。结论：针对女性的风险因素和预防策略，以及针对性别和性别的心脏病治疗和结果，考虑到所有研究支柱的生命过程问题，国际投入多样化，优先进行研究。

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An International Perspective on Priority Areas for Women’s Cardiovascular Health Research: Qualitative Findings From a Cross-Sectional Survey

Background

The Global Cardiovascular Research Funders Forum (GCRFF) unites international research funders interested in supporting cardiovascular disease (CVD) research. One focus area is women’s cardiovascular health; the present study aimed to identify priority themes for future joint research funding opportunities.

Methods

After ethics approval, a survey was developed based on literature review, GCRFF feedback, and input from methodologists/content experts. The survey comprised 3 open-ended and 5 multiple-choice questions. With the use of widespread dissemination strategies, an electronic survey portal was opened for 8 weeks, from November 15, 2023, to January 15, 2024, with various language options. Results were downloaded into a secure REDCap database for analysis. Independent theming of responses was completed by 3 reviewers until coding consensus was achieved, following which 1 coder completed the remaining theming. Descriptive statistics are reported.

Results

Among the 191 responses, all 9 GCRFF countries were represented. Most respondents identified as women (74%) and clinicians/academics (77%); fewer people with lived or living experience participated (23%). Common themes included women-specific risk factors and prevention strategies (56%), life-course issues (43%), and sex- and gender-specific treatments and outcomes (36%). Common topics were CVD (66%), coronary artery disease (CAD) (18%), and heart disease (13%). Designated research pillars included clinical (52%), population health (36%), and basic science (30%). Solutions proposed included knowledge generation (71%), increased funding (55%), networking researchers (52%), and knowledge mobilisation (41%). Congruence of priority ordering was demonstrated between sex and respondent residence subgroups.

Conclusion

Diverse international input prioritised research in risk factors and prevention strategies specific to women and in sex- and gender-specific treatment and outcomes of heart disease, with considerations of life-course issues across all research pillars.

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