拓扑结构驱动细胞命运

IF 17.6 1区物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY

Nature Physics Pub Date : 2025-03-13 DOI:10.1038/s41567-025-02809-9

Timothy E. Saunders

引用次数: 0

摘要

细胞在发育过程中根据遗传或机械的因素决定了特定的命运。现在研究表明，在果蝇胚胎中，细胞核迁移到外皮层或保持内化的决定取决于拓扑结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Topology drives cell fate

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Topology drives cell fate

Cells take on specific fates during development based on cues, which can be genetic or mechanical. Now it is shown that the decision of cell nuclei to either migrate to the outer cortex or remain internalized in fruit fly embryos depends on topology.

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来源期刊

Nature Physics 物理-物理：综合

CiteScore

30.40

自引率

2.00%

发文量

349

审稿时长

4-8 weeks

期刊介绍： Nature Physics is dedicated to publishing top-tier original research in physics with a fair and rigorous review process. It provides high visibility and access to a broad readership, maintaining high standards in copy editing and production, ensuring rapid publication, and maintaining independence from academic societies and other vested interests. The journal presents two main research paper formats: Letters and Articles. Alongside primary research, Nature Physics serves as a central source for valuable information within the physics community through Review Articles, News & Views, Research Highlights covering crucial developments across the physics literature, Commentaries, Book Reviews, and Correspondence.