双相情感障碍的全球老龄化和老年实验（GAGE-BD）：建立一个全球联盟，使双相情感障碍患者在晚年受益。

IF 5.5 2区医学 Q1 PSYCHIATRY

Current Psychiatry Reports Pub Date : 2025-05-01 Epub Date: 2025-03-11 DOI:10.1007/s11920-025-01593-w

Melis Orhan, Laura Montejo, Martha Sajatovic, Lisa Eyler, Annemiek Dols

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引用次数: 0

摘要

回顾的目的：回顾了全球老年双相情感障碍（age - bd）项目的研究结果，包括来自全球老年双相情感障碍（OABD）和健康参与者（约N = 5000）的社会人口学和临床信息。在多个波中收集数据，以创建一个大型集成数据集。最近的研究发现：双相障碍似乎不会随着年龄的增长而消退。BD亚型和早/晚发病在日常功能上无显著差异。与对照组相比，OABD患者的身体合并症更为常见。患有OABD的女性发病年龄更早，精神科住院治疗次数更多。GAGE-BD是最大的OABD队列。数据集结果为了解BD的长期发展轨迹和该人群的特定需求提供了独特而全面的资源。研究结果对于指导未来的研究和改善老年双相障碍患者的护理策略至关重要。

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Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD): Building a Global Consortium Benefiting People with Bipolar Disorder in Later Life.

Purpose of review: Findings from the Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) project, including sociodemographic and clinical information from older age bipolar disorder (OABD) and healthy participants around the globe (approximately N = 5000) were reviewed. Data was collected in multiple waves to create a large integrated dataset.

Recent findings: BD does not seem to fade with age. BD subtype and early/late onset did not show significant differences in daily functioning. Physical comorbidities were more frequent in OABD compared with controls. Women with OABD had an earlier age at onset and more psychiatric hospitalizations. GAGE-BD is the largest OABD cohort. Dataset results offer a unique and comprehensive resource for understanding the long-term trajectory of BD and the specific needs of this population. Findings are vital for guiding future research and improving care strategies for aging individuals with BD.

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来源期刊

Current Psychiatry Reports PSYCHIATRY-

CiteScore

11.30

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published research in psychiatry. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by psychiatric disorders. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anxiety, medicopsychiatric disorders, and schizophrenia and other related psychotic disorders. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.