皮质激素浸润在骨关节疾病中的短期和长期疗效。2年前瞻性研究

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
José Miguel Baena-Díez , Meng Ting Sun-Ni , Manel García-Lareo , Maria Barroso-Sevillano , Helena Gárate-Ercilla , Eva Rodriguez-Perez , en representación del Grupo de Estudio de Infiltraciones en Atención Primaria (GEIAP)
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引用次数: 0

摘要

主要目的评价皮质类固醇注射的近期和长期疗效及安全性。设计描述性、前瞻性研究。位置:城市全科医疗中心。参与者:经历药物治疗失败且视觉模拟量表(VAS)疼痛评分≥4分的成年患者(年龄18岁)。干预措施:给予曲安奈德注射,最多3次。主要测量:短期成功定义为VAS评分降低≥3分。长期成功定义为6、12、18和24个月无症状复发,并评估任何并发症。结果共注射皮质类固醇345次。患者平均年龄58.8岁,女性占73%。治疗的最常见疾病包括肩袖疾病(38.3%)、足底筋膜炎(16.5%)、转子滑囊炎(15.7%)、上髁炎(11.6%)和鹅肝滑囊炎(9.6%)。78.6%的注射短期成功,VAS平均降低4.4点(95% CI: 4.1-4.7)。对于原发性疾病,VAS评分降低超过4分。长期成功率为6个月73.3%,12个月64.6%,18个月60.6%,24个月56.5% (P <;0.001)。24个月时,成功率分别为:肩袖疾病(49.2%)、足底筋膜炎(49.1%)、转子滑囊炎(66.7%)、上髁炎(47.5%)和鹅肝滑囊炎(84.8%)。总并发症发生率为1.2%,均为轻微并发症。结论皮质类固醇注射治疗骨关节疾患短期有效、安全。然而,有效性在2年内逐渐下降,结果因具体病理而异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efectividad a corto y largo plazo de las infiltraciones con corticoides en dolencia osteoarticular. Estudio prospectivo a 2 años

Main objective

To evaluate the short- and long-term effectiveness and safety of corticosteroid injections.

Design

Descriptive, prospective study.

Location

Urban general practice centre.

Participants

Adult patients (age >18 years) who experienced failure of medical treatment and reported pain scores ≥4 on the Visual Analogue Scale (VAS).

Interventions

Patients received injections of triamcinolone acetonide, maximum 3 injections.

Main measurements

Short-term success was defined as a reduction of ≥3 points on the VAS. Long-term success was defined as the absence of symptom recurrence at 6, 12, 18, and 24 months, with an assessment of any complications.

Results

A total of 345 corticosteroid injections were administered. Patient's mean age was 58.8 years, and 73% were women. The most common conditions treated included rotator cuff disorders (38.3%), plantar fasciitis (16.5%), trochanteric bursitis (15.7%), epicondylitis (11.6%), and anserine bursitis (9.6%). 78.6% of injections were successful short term, with an average VAS reduction of 4.4 points (95% CI: 4.1-4.7). For the primary conditions, the VAS reduction exceeded 4 points. Long-term success rates were 73.3% at 6 months, 64.6% at 12 months, 60.6% at 18 months, and 56.5% at 24 months (P < 0.001). At 24 months, the success rates were: rotator cuff disorders (49.2%), plantar fasciitis (49.1%), trochanteric bursitis (66.7%), epicondylitis (47.5%), and anserine bursitis (84.8%). The overall complication rate was 1.2%, all being minor.

Conclusions

Corticosteroid injections are highly effective and safe for managing osteoarticular conditions short term. However, the effectiveness declines progressively over 2 years, with outcomes varying depending on the specific pathology.
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来源期刊
Atencion Primaria
Atencion Primaria 医学-医学:内科
CiteScore
2.90
自引率
8.00%
发文量
156
审稿时长
33 days
期刊介绍: Atención Primaria es una revista que publica trabajos de investigación relativos al ámbito de la atención primaria de salud. Desde el punto de vista conceptual, Atención Primaria asume el nuevo modelo de atención primaria de salud, orientado no sólo a la curación de la enfermedad, sino también a su prevención y a la promoción de la salud, tanto en el plano individual como en el de la familia y la comunidad. En estos nuevos aspectos que definen el modelo de atención primaria de salud es en los que se centran los trabajos de investigación que publica Atención Primaria, la primera revista de originales española creada para recoger y difundir la producción científica realizada desde los centros de atención primaria de salud sobre cuestiones como protocolización de la asistencia, programas de prevención, seguimiento y control de pacientes crónicos, organización y gestión de la asistencia primaria, entre otros.
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