克罗恩病患者ustekinumumab诱导的血管炎

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-03-05 eCollection Date: 2025-03-01 DOI:10.14309/crj.0000000000001625

Luis E Ospina Velasquez, Konstantinos A Papadakis, Siri A Urquhart

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引用次数: 0

摘要

免疫球蛋白A血管炎（IgAV）是一种免疫介导的疾病，通常涉及皮肤、肌肉骨骼、肾脏和胃肠道系统。药物引起的IgAV病例是罕见的，文献记载很少。我们报告一例患者克罗恩病谁发展了一个招标，可触及的紫疹躯干和四肢3周后接受剂量的ustekinumab。该病例强调了在接受先进疗法治疗时出现皮肤症状的炎症性肠病患者考虑IgAV的重要性。

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Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease.

Immunoglobulin A vasculitis (IgAV) is an immune-mediated disorder that commonly involves dermatologic, musculoskeletal, renal, and gastrointestinal systems. Drug-induced cases of IgAV are rare and sparsely documented in the literature. We report a case of a patient with Crohn's disease who developed a tender, palpable purpuric rash on the torso and extremities 3 weeks after receiving a dose of ustekinumab. This case underscores the importance of considering IgAV in patients with inflammatory bowel disease who present with cutaneous symptoms while undergoing treatment with advanced therapies.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.