三路迷宫大鼠行为技能形成特点的研究

IF 4.033 Q4 Biochemistry, Genetics and Molecular Biology
S. P. Dragan, D. B. Komarov, I. A. Veselovsky, A. V. Bogomolov
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引用次数: 0

摘要

实验研究了在三向迷宫中不同队列的大鼠的行为技能的形成,包括学习主动回避条件反应的能力。为了确定训练最多的品种,选择了白杂种大鼠(100只)和朗埃文斯大鼠和小飞象大鼠(各30只)。条件刺激是在迷宫中随机选择的目标走廊中打开声音和关闭灯光的组合。在打开声音5 s后,关闭灯光,向非目标走廊提供无条件刺激(电流)并打开灯光。大鼠的任务是在声音刺激下过渡到迷宫的目标(安全)路径。到达目标后,从非目标走廊的地板上移除电压并关闭灯。条件刺激与无条件刺激组合的间隔时间为30 s,每种大鼠的训练时间为1个月,每天有20次刺激组合。每只大鼠被认为在不超过6秒的时间内有70%或更多的概率达到目标。人们发现,小飞象鼠最适合于对一大群老鼠进行快速训练,以对刺激性刺激作出反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Study of the Peculiarities of the Formation of Behavioral Skills in Rats in a Three-Way Maze

A Study of the Peculiarities of the Formation of Behavioral Skills in Rats in a Three-Way Maze

The formation of behavioral skills, consisting of the ability to learn the conditioned reaction of active avoidance, in different lines of rats in a three-way maze has been experimentally studied. To determine the most trained lines, white mongrel rats (100 individuals) and Long Evans and Dumbo rats (30 individuals each) were selected. The conditional stimulus was a combination of turning on a sound and turning off a light in a randomly selected target corridor of the maze. At 5 s after turning on the sound, the light was turned off, an unconditional stimulus (electric current) was supplied to the nontarget corridors and the light was turned on. The task of the rat was to make the transition to the target (safe) way of the maze in response to a sound stimulus. Upon reaching the target, the voltage was removed from the floor of the nontarget corridors and the lights were turned off. The pause between the combinations of conditional/unconditional stimulus was 30 s, the training time for each type of rat was 1 month with 20 presentations of combinations of stimuli per day. Each rat was considered trained with a probability of achieving the goal in 70% or more cases in a time not exceeding 6 s. It has been found that Dumbo rats were best suited for rapid training of large groups of rats to respond to an irritating stimulus.

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来源期刊
Biophysics
Biophysics Biochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
1.20
自引率
0.00%
发文量
67
期刊介绍: Biophysics is a multidisciplinary international peer reviewed journal that covers a wide scope of problems related to the main physical mechanisms of processes taking place at different organization levels in biosystems. It includes structure and dynamics of macromolecules, cells and tissues; the influence of environment; energy transformation and transfer; thermodynamics; biological motility; population dynamics and cell differentiation modeling; biomechanics and tissue rheology; nonlinear phenomena, mathematical and cybernetics modeling of complex systems; and computational biology. The journal publishes short communications devoted and review articles.
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