Lei Huang, Yang Zhou, Yan Liu, Peijun Xu, Xiaohong Deng
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引用次数: 0
摘要
目的:探讨自我效能感(SE)在类风湿关节炎(RA)患者服药依从性(MA)与疾病感知(IP)之间的中介作用。方法:采用方便抽样的方法,选取广州市两家医院收治的238例类风湿关节炎患者。采用一般信息问卷、慢性疾病SE量表、IP量表和药物依从性评定量表(MARS-A)进行横断面调查。采用R软件(4.2.2版)构建中介模型,考察SE和IP对RA患者MA的影响。采用自举法验证SE的中介作用。结果:IP、SE、MA平均得分分别为120.50±12.32、29.36±8.49、21.22±2.96。Pearson相关分析显示,SE与IP (r = 0.23, p < 0.01)、MA (r = 0.195, p < 0.001)呈正相关。IP与MA呈正相关(r = 0.532, p < 0.05)。证实了SE在IP和MA之间的中介作用。结论:SE在RA患者IP和MA之间起部分介导作用。
Medication Adherence and Illness Perception in Patients with Rheumatoid Arthritis: The Mediating Effect of Self-Efficacy.
Objectives: To explore the mediating effect of self-efficacy (SE) on the relationship between medication adherence (MA) and illness perception (IP) in patients with rheumatoid arthritis (RA).
Methods: A convenient sampling method was used to select 238 RA patients undergoing treatment at two hospitals in Guangzhou, China. A cross-sectional survey was conducted, utilizing a general information questionnaire, a chronic disease SE scale, an IP scale, and the Medication Adherence Rating Scale (MARS-A). R software (Version 4.2.2) was used to construct a mediation model to examine the impact of SE and IP on MA among RA patients. The bootstrap method was employed to validate the mediating role of SE.
Results: The average scores for IP, SE, and MA were 120.50 ± 12.32, 29.36 ± 8.49, and 21.22 ± 2.96, respectively. Pearson correlation analysis revealed that SE was positively correlated with IP (r = 0.23, p < 0.01) and MA (r = 0.195, p < 0.001). IP was also positively correlated with MA (r = 0.532, p < 0.05). The mediating effect of SE in the relationship between IP and MA was confirmed.
Conclusion: SE partially mediates the relationship between IP and MA in patients with RA.
期刊介绍:
The Journal of Musculoskeletal and Neuronal Interactions (JMNI) is an academic journal dealing with the pathophysiology and treatment of musculoskeletal disorders. It is published quarterly (months of issue March, June, September, December). Its purpose is to publish original, peer-reviewed papers of research and clinical experience in all areas of the musculoskeletal system and its interactions with the nervous system, especially metabolic bone diseases, with particular emphasis on osteoporosis. Additionally, JMNI publishes the Abstracts from the biannual meetings of the International Society of Musculoskeletal and Neuronal Interactions, and hosts Abstracts of other meetings on topics related to the aims and scope of JMNI.