新生儿重症监护室的婴儿补铁:什么制剂,多少,多长时间是最佳的?

IF 2.9 3区 医学 Q1 PEDIATRICS
Sandra Juul , Kendell German
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引用次数: 0

摘要

早产婴儿或有其他围产期危险因素的婴儿铁缺乏和铁超载的风险更大。围产期铁补充不足与长期的神经发育影响有关。基于此,铁补充剂必须针对婴儿的个人铁需求,以避免铁缺乏和超载的不利影响。多年来,肠内补铁一直是新生儿补铁的黄金标准。然而,新兴的肠外制剂可能为一些婴儿提供了另一种选择,例如那些不能耐受口服补充剂或对肠内补充剂难以耐受的婴儿。补充的最佳剂量和时间是一个正在进行的研究领域。在这篇综述中,我们将总结现有的肠内和肠外铁制剂,回顾铁的测量参数,并指出悬而未决的问题和正在进行的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Iron supplementation for infants in the NICU: What preparation, how much, and how long is optimal?
Infants born preterm or with other perinatal risk factors are at added risk for both iron deficiency and overload. Insufficient iron supplementation in the perinatal period is associated with long-term neurodevelopmental effects. Based on this, iron supplements must be targeted to infants’ individual iron needs to avoid the adverse effects of both iron deficiency and overload. Enteral iron supplements have been the gold standard in iron supplementation of neonates for many years. However, emerging parenteral formulations may provide an alternative for some infants, such as those who are unable to tolerate oral supplements or who are refractory to enteral supplementation. Optimal dosing and timing of supplementation is an area of ongoing research. In this review, we will summarize available enteral and parenteral iron formulations, review iron measurement parameters, and identify outstanding questions and ongoing research.
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来源期刊
CiteScore
6.40
自引率
3.30%
发文量
49
审稿时长
6-12 weeks
期刊介绍: Seminars in Fetal & Neonatal Medicine (formerly Seminars in Neonatology) is a bi-monthly journal which publishes topic-based issues, including current ''Hot Topics'' on the latest advances in fetal and neonatal medicine. The Journal is of interest to obstetricians and maternal-fetal medicine specialists. The Journal commissions review-based content covering current clinical opinion on the care and treatment of the pregnant patient and the neonate and draws on the necessary specialist knowledge, including that of the pediatric pulmonologist, the pediatric infectious disease specialist, the surgeon, as well as the general pediatrician and obstetrician. Each topic-based issue is edited by an authority in their field and contains 8-10 articles. Seminars in Fetal & Neonatal Medicine provides: • Coverage of major developments in neonatal care; • Value to practising neonatologists, consultant and trainee pediatricians, obstetricians, midwives and fetal medicine specialists wishing to extend their knowledge in this field; • Up-to-date information in an attractive and relevant format.
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