基于HEP和HRV的脑心相互作用反馈回路研究

IF 5.3 2区医学 Q1 ENGINEERING, BIOMEDICAL

Biocybernetics and Biomedical Engineering Pub Date : 2025-02-28 DOI:10.1016/j.bbe.2025.02.005

Shanshan Wang , Xiaoni Wang , Yuxin Zhao, Lin Xie, Jianbao Zhang

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引用次数: 0

摘要

尽管越来越多的证据表明心跳诱发电位（HEP）是内感受的生物标志物，但HEP与心血管功能的关系尚不清楚。本文设计了心算和冥想任务，分别激活交感神经和副交感神经活动，并记录了健康青年男性的脑电图和心血管参数。我们的研究结果表明，在心算过程中HEP会下降，而在冥想过程中则会增加。HEP和血压之间的相关性也被观察到，表明压力感受器拉伸可能有助于HEP的产生。此外，HEP与副交感神经活动呈正相关，与交感神经活动负相关。总的来说，这些结果表明，在HEP介导的大脑和心脏之间存在潜在的负反馈循环。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A feedback loop study of brain-heart interaction based on HEP and HRV

Although growing evidences suggest heartbeat evoked potential (HEP) as a biomarker of interoception, little is known about how HEP is related to cardiovascular function. In the article, mental arithmetic and meditation tasks that respectively activate sympathetic and parasympathetic activities were designed, and electroencephalogram and cardiovascular parameters were recorded in healthy young males. Our findings revealed a decrease in HEP during mental arithmetic and an increase during meditation. A correlation between HEP and blood pressure was also observed, indicating that baroreceptor stretch may contribute to HEP generation. Furthermore, HEP showed a positive correlation with parasympathetic activity and a negative correlation with sympathetic activity. Collectively, these results suggest the presence of a potential negative feedback loop between the brain and heart, mediated by HEP.

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来源期刊

Biocybernetics and Biomedical Engineering ENGINEERING, BIOMEDICAL-

CiteScore

16.50

自引率

6.20%

发文量

审稿时长

38 days

期刊介绍： Biocybernetics and Biomedical Engineering is a quarterly journal, founded in 1981, devoted to publishing the results of original, innovative and creative research investigations in the field of Biocybernetics and biomedical engineering, which bridges mathematical, physical, chemical and engineering methods and technology to analyse physiological processes in living organisms as well as to develop methods, devices and systems used in biology and medicine, mainly in medical diagnosis, monitoring systems and therapy. The Journal''s mission is to advance scientific discovery into new or improved standards of care, and promotion a wide-ranging exchange between science and its application to humans.