丝绸敷料在皮肤损伤治疗中的应用：系统综述

IF 3.2 3区医学 Q2 CRITICAL CARE MEDICINE

Burns Pub Date : 2025-02-14 DOI:10.1016/j.burns.2025.107426

Leen Vermoesen , Ignace De Decker , Jozef Verbelen , Henk Hoeksema , Kimberly De Mey , Petra De Coninck , Julie van Durme , Nathalie Roche , Stan Monstrey , Karel E.Y. Claes

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引用次数: 0

摘要

皮肤损伤，如浅表烧伤和皮肤移植供体目前使用各种敷料处理。常见的挑战包括换药时的不适和创伤，不理想的愈合和明显的疤痕。丝绸敷料通过减少频繁更换的需要显示出希望，由于其透明度，允许伤口评估，发挥抗菌性能，并最大限度地减少疤痕。然而，蚕丝尚未广泛应用于临床。方法进行系统评价。根据PRISMA指南对PubMed、Embase、Cochrane Library 3个数据库进行检索。仅纳入随机对照试验、队列研究、病例对照研究和病例系列。进行了适当的质量测试。结果共识别1373个搜索结果。重复数据删除后，按标题和摘要筛选979篇，其中保留全文20篇，最终纳入9篇。检查的参数包括：愈合时间、疼痛、主观和客观皮肤测量、不良事件、感染率、透明度和价格。结论真丝敷料在透明度、愈合时间、疼痛、红斑、色素沉着、水分流失正常化、紧致度、粘弹性恢复、微循环、不良事件和感染率等方面与现有敷料具有相当的疗效。它们是治疗浅表部分厚度皮肤烧伤和皮肤移植供体部位的一种经济有趣的替代方法。然而，需要更大规模的高质量研究来证实这些发现。

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The use of silk dressings in the treatment of skin injuries: A systematic review

Background

Skin injuries like superficial burns and skin graft donor sites are currently managed using various dressings. Frequent challenges include discomfort and trauma during dressing changes, suboptimal healing and significant scarring. Silk dressings show promise by reducing the need for frequent changes, allowing wound evaluation due to its transparency, exerting antibacterial properties, and minimizing scarring. However, silk is not yet widely adopted in clinical settings.

Methods

A systematic review was conducted. A search through 3 databases (PubMed, Embase, Cochrane Library) according to the PRISMA guidelines was performed. Only RCTs, cohort studies, case-control studies and case series were included. Appropriate quality tests were performed.

Results

1373 search results were identified. After deduplication, 979 were screened by title and abstract, of which 20 full-text articles remained and ultimately, 9 articles were included. Parameters examined were: healing duration, pain, subjective and objective skin measurements, adverse events, infection rates, transparency and price.

Conclusion

Silk dressings demonstrate comparable efficacy to existing dressings concerning transparency, healing time, pain, erythema, pigmentation, water loss normalization, firmness, visco-elasticity recovery, microcirculation, adverse events and infection rates. They are an economically interesting alternative for managing superficial partial-thickness skin burns and skin graft donor sites. Nonetheless, larger high-quality studies are needed to confirm these findings.

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来源期刊

Burns 医学-皮肤病学

CiteScore

4.50

自引率

18.50%

发文量

304

审稿时长

72 days

期刊介绍： Burns aims to foster the exchange of information among all engaged in preventing and treating the effects of burns. The journal focuses on clinical, scientific and social aspects of these injuries and covers the prevention of the injury, the epidemiology of such injuries and all aspects of treatment including development of new techniques and technologies and verification of existing ones. Regular features include clinical and scientific papers, state of the art reviews and descriptions of burn-care in practice. Topics covered by Burns include: the effects of smoke on man and animals, their tissues and cells; the responses to and treatment of patients and animals with chemical injuries to the skin; the biological and clinical effects of cold injuries; surgical techniques which are, or may be relevant to the treatment of burned patients during the acute or reconstructive phase following injury; well controlled laboratory studies of the effectiveness of anti-microbial agents on infection and new materials on scarring and healing; inflammatory responses to injury, effectiveness of related agents and other compounds used to modify the physiological and cellular responses to the injury; experimental studies of burns and the outcome of burn wound healing; regenerative medicine concerning the skin.