神经性疼痛复合纳米镇痛药的病理生理导向工程研究(Sci. 8/2025)

IF 14.1 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Wenkai Wang, Yan Wang, Xinle Huang, Peng Wu, Lanlan Li, Yang Zhang, Yihui Chen, Zhiyu Chen, Changqing Li, Yue Zhou, Jianxiang Zhang
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引用次数: 0

摘要

在文章编号2405483中,周岳、张建祥等报道了一种由消炎纳米胶束和靶向钙通道α2δ1亚基的镇痛肽组成的联合纳米镇痛药。这种创新的纳米疗法有效地抑制神经炎症,促进神经再生,并提供镇痛活性,从而为神经损伤引起的神经性疼痛的治疗提供协同效应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025)

Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025)

Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025)

Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025)

Combination Nanoanalgesic for Neuropathic Pain

In article number 2405483, Yue Zhou, Jianxiang Zhang, and co-workers report a combination nanoanalgesic composed of inflammation-resolving nanomicelles and an analgesic peptide targeting the calcium channel α2δ1 subunit. This innovative nanotherapy effectively inhibits neuroinflammation, promotes nerve regeneration, and provides analgesic activity, thereby affording synergistic effects for the treatment of neuropathic pain induced by nerve injury.

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来源期刊
Advanced Science
Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
18.90
自引率
2.60%
发文量
1602
审稿时长
1.9 months
期刊介绍: Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.
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