巴黎多花植物中的甾体化合物：结构、生物活性和生物合成

IF 8.3 2区生物学 Q1 PLANT SCIENCES

Current opinion in plant biology Pub Date : 2025-02-18 DOI:10.1016/j.pbi.2025.102695

Xin Hua , Chengxi Kou , Fengge Wang , Jianfeng Zhang , Jifeng Yuan , Zheyong Xue

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Steroidal compounds in Paris polyphylla:structure, biological activities, and biosynthesis

Steroidal compounds are chemical constituents found in the traditional medicinal plant Paris polyphylla, known for their significant pharmacological activities. Due to their complex structures, the biosynthetic pathways of these compounds have garnered considerable attention. In recent years, substantial progress has been made in elucidating the biosynthetic pathways of steroidal compounds from P. polyphylla, with several complete biosynthetic routes being fully characterized. The de novo synthesis of diosgenin has been successfully achieved in both Saccharomyces cerevisiae and Nicotiana benthamiana using various metabolic engineering techniques. Herein, we summarize the latest research progress regarding the structural classification, biological activities, and biosynthesis studies of steroidal compounds from P. polyphylla.

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来源期刊

Current opinion in plant biology 生物-植物科学

CiteScore

16.30

自引率

3.20%

发文量

131

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Plant Biology builds on Elsevier's reputation for excellence in scientific publishing and long-standing commitment to communicating high quality reproducible research. It is part of the Current Opinion and Research (CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy - of editorial excellence, high-impact, and global reach - to ensure they are a widely read resource that is integral to scientists' workflow.