Jared J Tuttle, Shannon D Scarboro, John C Fitzpatrick, C Armitage Harper
{"title":"推测丝裂霉素c在白内障和Xen凝胶支架联合手术后引起视网膜毒性。","authors":"Jared J Tuttle, Shannon D Scarboro, John C Fitzpatrick, C Armitage Harper","doi":"10.1097/ICB.0000000000001729","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To describe a case of presumed MMC-induced retinal toxicity following combined cataract and Xen gel stent surgery.</p><p><strong>Methods: </strong>Observational case report.</p><p><strong>Results: </strong>A 66-year-old male presents with progressive vision loss (20/25 baseline to light-perception (LP)) following combined cataract and Xen gel stent surgery in the left eye. The patient received 0.15 ml of 0.4 mg/ml of MMC via intra-tenon injection during the surgery. The patient reported severe eye pain following surgery which gradually resolved over time. Upon examination at post-operative day 41, vessel attenuation, sclerotic vessels, and optic nerve pallor are observed without any retinal hemorrhaging. At post-operative day 55, visual acuity remains at LP with a flat line electroretinogram. Outcomes remain consistent at postoperative day 125.</p><p><strong>Conclusion: </strong>Care should be taken to avoid intraocular MMC, especially when administered via intra-tenon injection during combined cataract and Xen gel stent surgery.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Presumed Mitomycin C-Induced Retinal Toxicity Following Combined Cataract and Xen Gel Stent Surgery.\",\"authors\":\"Jared J Tuttle, Shannon D Scarboro, John C Fitzpatrick, C Armitage Harper\",\"doi\":\"10.1097/ICB.0000000000001729\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To describe a case of presumed MMC-induced retinal toxicity following combined cataract and Xen gel stent surgery.</p><p><strong>Methods: </strong>Observational case report.</p><p><strong>Results: </strong>A 66-year-old male presents with progressive vision loss (20/25 baseline to light-perception (LP)) following combined cataract and Xen gel stent surgery in the left eye. The patient received 0.15 ml of 0.4 mg/ml of MMC via intra-tenon injection during the surgery. The patient reported severe eye pain following surgery which gradually resolved over time. Upon examination at post-operative day 41, vessel attenuation, sclerotic vessels, and optic nerve pallor are observed without any retinal hemorrhaging. At post-operative day 55, visual acuity remains at LP with a flat line electroretinogram. Outcomes remain consistent at postoperative day 125.</p><p><strong>Conclusion: </strong>Care should be taken to avoid intraocular MMC, especially when administered via intra-tenon injection during combined cataract and Xen gel stent surgery.</p>\",\"PeriodicalId\":53580,\"journal\":{\"name\":\"Retinal Cases and Brief Reports\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Retinal Cases and Brief Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/ICB.0000000000001729\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Retinal Cases and Brief Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ICB.0000000000001729","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Presumed Mitomycin C-Induced Retinal Toxicity Following Combined Cataract and Xen Gel Stent Surgery.
Purpose: To describe a case of presumed MMC-induced retinal toxicity following combined cataract and Xen gel stent surgery.
Methods: Observational case report.
Results: A 66-year-old male presents with progressive vision loss (20/25 baseline to light-perception (LP)) following combined cataract and Xen gel stent surgery in the left eye. The patient received 0.15 ml of 0.4 mg/ml of MMC via intra-tenon injection during the surgery. The patient reported severe eye pain following surgery which gradually resolved over time. Upon examination at post-operative day 41, vessel attenuation, sclerotic vessels, and optic nerve pallor are observed without any retinal hemorrhaging. At post-operative day 55, visual acuity remains at LP with a flat line electroretinogram. Outcomes remain consistent at postoperative day 125.
Conclusion: Care should be taken to avoid intraocular MMC, especially when administered via intra-tenon injection during combined cataract and Xen gel stent surgery.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
