Alec M Giakas, Alexandra L Hohmann, Nikhil N Mehta, Julia M Dambly, Jess H Lonner
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引用次数: 0
摘要
对于移位性股骨颈骨折的治疗是采用半髋关节置换术还是全髋关节置换术存在争议。本研究旨在比较这些方法的随机对照试验(rct)的脆弱性指数(FI)。我们查询了这些包含二分类结果的随机对照试验,发现11个随机对照试验有63个二分类结果。所有结果的中位FI为6,表明6次事件逆转将改变结果的统计显著性。显著结果的中位FI为2,不显著结果的中位FI为6,表明偏向一种手术方法的结果在统计学上比证明等效的结果更脆弱。[矫形手术。202 x; 4 x (x): xx-xx。]。
The Fragility of Statistical Findings Regarding Hemiarthroplasty Versus Total Hip Arthroplasty for Displaced Femoral Neck Fractures.
There is debate over the treatment of displaced femoral neck fractures with either hemiarthroplasty or total hip arthroplasty. This study aimed to evaluate the fragility index (FI) of randomized controlled trials (RCTs) comparing these methods. We queried for these RCTs containing dichotomous outcomes, finding 11 RCTs with 63 dichotomous outcomes. The median FI for all outcomes was 6, signifying that 6 event reversals would change the statistical significance of an outcome. The median FI was 2 for significant outcomes and 6 for nonsignificant outcomes, indicating that outcomes favoring one surgical method are more statistically fragile than those demonstrating equivalency. [Orthopedics. 2025;48(2):69-73.].
期刊介绍:
For over 40 years, Orthopedics, a bimonthly peer-reviewed journal, has been the preferred choice of orthopedic surgeons for clinically relevant information on all aspects of adult and pediatric orthopedic surgery and treatment. Edited by Robert D''Ambrosia, MD, Chairman of the Department of Orthopedics at the University of Colorado, Denver, and former President of the American Academy of Orthopaedic Surgeons, as well as an Editorial Board of over 100 international orthopedists, Orthopedics is the source to turn to for guidance in your practice.
The journal offers access to current articles, as well as several years of archived content. Highlights also include Blue Ribbon articles published full text in print and online, as well as Tips & Techniques posted with every issue.