头颈癌的光免疫治疗：系统综述

IF 1.6 4区医学 Q2 OTORHINOLARYNGOLOGY

Auris Nasus Larynx Pub Date : 2025-02-13 DOI:10.1016/j.anl.2025.01.005

Isaku Okamoto

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引用次数: 0

摘要

光免疫疗法是一种新的癌症治疗方法，使用西妥昔单抗与光活化染料IR700的缀合物西妥昔单抗沙罗他罗坎钠和波长为690nm的红光。在日本，自2021年起，“不可切除的局部晚期或局部复发的头颈癌”的光免疫治疗已纳入保险范围。虽然目前仅被批准用于头颈部癌症，但光免疫疗法是未来各种癌症治疗的重要技术。光免疫疗法是未来各种癌症治疗的重要技术，争取光免疫疗法在临床的发展和广泛应用是十分必要的。在本文中，我们将阐述光免疫治疗的机制、治疗病例、临床试验数据、来自日本的真实世界数据报告以及在实际临床实践中看到的未来问题和前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Photoimmunotherapy for head and neck cancer: A systematic review

Photoimmunotherapy is a new cancer treatment that uses cetuximab sarotalocan sodium, a conjugate of cetuximab and the light activatable dye, IR700, and red light at a wavelength of 690 nm.

In Japan, photoimmunotherapy for “unresectable locally advanced or locally recurrent head and neck cancer” has been covered by insurance since 2021. Although presently approved only for head and neck cancer, photoimmunotherapy is an important technology in the future of various cancer treatments. Photoimmunotherapy is an important technology for the future of various cancer treatments, and it is essential to strive for the development and widespread use of photoimmunotherapy in clinical practice.

In this review, we will explain the mechanism of photoimmunotherapy, treatment cases, clinical trial data, reports from real world data in Japan, and future issues and prospects as seen in actual clinical practice.

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来源期刊

Auris Nasus Larynx 医学-耳鼻喉科学

CiteScore

3.40

自引率

5.90%

发文量

169

审稿时长

30 days

期刊介绍： The international journal Auris Nasus Larynx provides the opportunity for rapid, carefully reviewed publications concerning the fundamental and clinical aspects of otorhinolaryngology and related fields. This includes otology, neurotology, bronchoesophagology, laryngology, rhinology, allergology, head and neck medicine and oncologic surgery, maxillofacial and plastic surgery, audiology, speech science. Original papers, short communications and original case reports can be submitted. Reviews on recent developments are invited regularly and Letters to the Editor commenting on papers or any aspect of Auris Nasus Larynx are welcomed. Founded in 1973 and previously published by the Society for Promotion of International Otorhinolaryngology, the journal is now the official English-language journal of the Oto-Rhino-Laryngological Society of Japan, Inc. The aim of its new international Editorial Board is to make Auris Nasus Larynx an international forum for high quality research and clinical sciences.