基于纳米医学的组织再生免疫疗法

IF 9.6 1区 医学 Q1 DERMATOLOGY
Song Li, Li Lu, Yuan Xiong, Jun Xiao
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引用次数: 0

摘要

组织再生是修复和恢复受损组织的必要条件,对临床结果具有重要意义。了解细胞机制和免疫系统在这一过程中的作用为改进再生技术提供了基础。纳米医学的出现通过引入纳米级技术,提供对治疗递送和细胞相互作用的精确控制,推动了这一领域的发展。通过调节免疫应答,各种免疫治疗方法,包括细胞因子治疗和免疫检查点抑制剂,可以建立组织修复的最佳环境。本文综述了纳米医学免疫治疗在组织再生中的研究进展及应用。重点介绍了纳米医学在免疫治疗中的特性和优势,讨论了纳米复合生物材料用于组织工程的最新进展,并提出了这一领域的挑战和未来发展方向。本文综述了纳米医学免疫治疗在组织工程中的应用前景,为下一代纳米医学在再生医学中的功能设计和战略发展提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanomedicine-based immunotherapy for tissue regeneration
Tissue regeneration is essential for repairing and restoring damaged tissues, which has significant implications for clinical outcomes. Understanding the cellular mechanisms and the role of the immune system in this process provides a basis for improved regenerative techniques. The emergence of nanomedicine has advanced this field by introducing nanoscale technology that offer precise control over therapeutic delivery and cellular interactions. By modulating immune responses, various immunotherapeutic approaches, including cytokine therapy and immune checkpoint inhibitors, can establish an optimal environment for tissue repair. This review summarizes recent findings and applications of nanomedicine-based immunotherapy in tissue regeneration. It highlights the properties and advantages of nanomedicine in immunotherapy, discusses recent progress in using nanocomposite biomaterials for tissue engineering, and addresses the challenges and future directions in this evolving field. This review aims to emphasize the promising potential of nanomedicine-based immunotherapy in tissue engineering, thereby contributing to the functional design and strategic development of next-generation nanomedicine for regenerative medicine.
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来源期刊
Burns & Trauma
Burns & Trauma 医学-皮肤病学
CiteScore
8.40
自引率
9.40%
发文量
186
审稿时长
6 weeks
期刊介绍: The first open access journal in the field of burns and trauma injury in the Asia-Pacific region, Burns & Trauma publishes the latest developments in basic, clinical and translational research in the field. With a special focus on prevention, clinical treatment and basic research, the journal welcomes submissions in various aspects of biomaterials, tissue engineering, stem cells, critical care, immunobiology, skin transplantation, and the prevention and regeneration of burns and trauma injuries. With an expert Editorial Board and a team of dedicated scientific editors, the journal enjoys a large readership and is supported by Southwest Hospital, which covers authors'' article processing charges.
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