皮肤神经内血管球瘤1例。

IF 1.6 4区 医学 Q3 DERMATOLOGY
Diana Frimpong, Sahar Naz, Murtaza Kadhum, Magdalena Rogut, Taiba Farooque, Jennifer O'Neill, Ann Fleming
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引用次数: 0

摘要

皮肤神经内血管球瘤在文献中被描述了两次,仍然是一种罕见的现象。我们提出的情况下,一个痛苦的皮肤病变的背部一个77岁的男子。组织病理学检查发现一个实性真皮结节位于扩张的周围神经内。免疫组织化学证实了形态学上的发现:被神经束包裹的平滑肌肌动蛋白(SMA)阳性结节显示S100阳性,周围有上皮膜抗原(EMA)阳性的神经细胞。这些发现与先前报道的皮肤神经内球瘤病例一致,在疼痛皮肤病变的鉴别诊断中应考虑这一实体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Cutaneous Intraneural Glomus Tumor

The cutaneous intraneural glomus tumor has been described twice in the literature and remains a rare phenomenon. We present the case of a painful cutaneous lesion on the back of a 77-year-old man. Histopathologic examination of the resected lesion revealed a solid dermal nodule set within an expanded peripheral nerve. Immunohistochemistry confirmed the morphological findings with an Smooth Muscle Actin (SMA) positive nodule encased by nerve fascicles demonstrating S100 positivity with a peripheral layer of Epithelial Membrane Antigen (EMA) positive perineural cells. These findings are in keeping with the previous reported cases of cutaneous intraneural glomus tumors and this entity should be considered in the differential diagnosis of painful cutaneous lesions.

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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
174
审稿时长
3-8 weeks
期刊介绍: Journal of Cutaneous Pathology publishes manuscripts broadly relevant to diseases of the skin and mucosae, with the aims of advancing scientific knowledge regarding dermatopathology and enhancing the communication between clinical practitioners and research scientists. Original scientific manuscripts on diagnostic and experimental cutaneous pathology are especially desirable. Timely, pertinent review articles also will be given high priority. Manuscripts based on light, fluorescence, and electron microscopy, histochemistry, immunology, molecular biology, and genetics, as well as allied sciences, are all welcome, provided their principal focus is on cutaneous pathology. Publication time will be kept as short as possible, ensuring that articles will be quickly available to all interested in this speciality.
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