了解真菌植物病原体中的货物分类和膜泡的相互作用:目前的知识和研究空白

IF 5.7 2区 生物学 Q1 MYCOLOGY
Manchela F. Ratsoma , Quentin C. Santana , Brenda D. Wingfield , Emma T. Steenkamp , Thabiso E. Motaung
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引用次数: 0

摘要

所有生物都会释放膜囊,这是一种由脂质双分子层组成的微小球形结构。这些囊泡具有多种功能,如形成新的细胞膜,从细胞中清除废物,运输脂质和其他物质。囊泡中通常包含的有效载荷通过运输所需的内体分选复合体(ESCRT)途径逐步进行分类。此外,这种膜系统的改变减少了囊泡的形成,并产生异常的内体室。在致病性真菌中,产生ESCRT基因破坏的突变体的研究表明对毒力和生长有负面影响。尽管有这些重要的作用,迄今为止只有少数真菌物种对ESCRT途径进行了评估。本文综述了ESCRT真菌通路及其在植物真菌发病机制中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Understanding cargo sorting and interactive effects of membrane vesicles in fungal phytopathogens: Current knowledge and research gaps
Organisms from all kingdoms of life release membrane vesicles, which are tiny, spherical structures made of a lipid bilayer. These vesicles carry out several functions, such as forming new cell membranes, removing waste products from the cell, and transporting lipids and other substances. The payloads often contained in the vesicles are sorted via the endosomal sorting complex required for transport (ESCRT) pathway stepwise. Furthermore, alterations to this endomembrane system reduces formation of vesicles and produce aberrant endosomal compartments. In pathogenic fungi, studies that have generated mutants with disruption in the ESCRT genes demonstrated negative effects on virulence and growth. Despite these important roles, only a few fungal species have to date been evaluated for the ESCRT pathway. In this review, we comprehensively evaluate recent developments in the ESCRT fungal pathway and its role in plant fungal pathogenesis.
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来源期刊
CiteScore
10.60
自引率
0.00%
发文量
36
期刊介绍: Fungal Biology Reviews is an international reviews journal, owned by the British Mycological Society. Its objective is to provide a forum for high quality review articles within fungal biology. It covers all fields of fungal biology, whether fundamental or applied, including fungal diversity, ecology, evolution, physiology and ecophysiology, biochemistry, genetics and molecular biology, cell biology, interactions (symbiosis, pathogenesis etc), environmental aspects, biotechnology and taxonomy. It considers aspects of all organisms historically or recently recognized as fungi, including lichen-fungi, microsporidia, oomycetes, slime moulds, stramenopiles, and yeasts.
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