超说明书使用特立帕肽治疗一例年轻患者椎体爆裂骨折：1例报告及文献回顾。

Q4 Medicine

Trauma Case Reports Pub Date : 2025-02-01 DOI:10.1016/j.tcr.2025.101127

Tiziano Villa , Vincenzo Zottola , Carlo Mariani , Alberto Borgonovo , Luciano Redenti

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引用次数: 0

摘要

我们描述了一例40岁男性患者L2椎体爆裂骨折，无任何其他合并症，原因是从马背上摔下来。由于创伤后40天CT上未见骨折愈合，手术介入L1-L3脊柱融合被认为是治疗的选择，但保守的非标签治疗被决定为5个月服用特利帕肽和补充维生素D -钙，并辅以夜间脉冲电磁场。5个月后骨折完全愈合。这是首次成功使用特立帕肽联合脉冲电磁场治疗年轻患者突发性椎体骨折而无需手术干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Off-label use of teriparatide for the treatment of a vertebral burst fracture in a young patient: A case report and literature review

We describe a case of L2 vertebral burst fracture in a 40-year-old male patient without any other comorbidities due to a ground-fall from horse. Despite surgical intervention with L1-L3 spine fusion was indicated as the treatment of choice since no fracture healing was visible on CT after 40 days post trauma, a conservative off-label therapy was decided with 5-month administration of teriparatide and vitamin D‑calcium supplementation together with nocturnal pulsed electro-magnetic field. Complete fracture healing was obtained after 5 months.

This is the first report of successful off-label use of teriparatide together with pulsed electro-magnetic field for the treatment of a burst vertebral fracture without surgical intervention in a young patient.

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来源期刊

Trauma Case Reports Medicine-Emergency Medicine

CiteScore

0.60

自引率

0.00%

发文量

131

审稿时长

26 weeks

期刊介绍： Trauma Case Reports is the only open access, online journal dedicated to the publication of case reports in all aspects of trauma care and accident surgery. Case reports on all aspects of trauma management, surgical procedures for all tissues, resuscitation, anaesthesia and trauma and tissue healing will be considered for publication by the international editorial team and will be subject to peer review. Bringing together these cases from an international authorship will shed light on surgical problems and help in their effective resolution.