原发性抗磷脂综合征导致其他健康年轻女性严重肢体缺血并最终截肢。

IF 0.5 4区 医学 Q4 ORTHOPEDICS
Katherine Lyons, Ronald Adelman, Vanessa Adelman, Britney Wenig
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引用次数: 0

摘要

本病例报告描述了一名健康的43岁女性,因抗磷脂综合征继发外周动脉血栓形成而出现严重疼痛、足下垂和严重的左脚肢体缺血。抗磷脂综合征是一种自身免疫性疾病,经常表现为复发性动脉和/或静脉血栓形成事件、缺血性中风和流产。与静脉血栓形成相比,主要影响动脉的抗磷脂综合征不太常见。我们的患者接受了几次血管手术干预和抗凝治疗;尽管如此,由于缺血恶化,她最终接受了膝盖以下截肢手术。本病例报告的目的是强调抗磷脂综合征应与动脉缺血事件(如无其他已知原因的严重肢体缺血)相区分,并应通过跨专业团队的方法进行治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary Antiphospholipid Syndrome Causing Critical Limb Ischemia and Ultimately Amputation in an Otherwise Healthy Young Female.

This case report describes an otherwise healthy 43-year-old female who presented with severe pain, foot drop, and critical limb ischemia to her left foot caused by thrombosis of a peripheral artery secondary to antiphospholipid syndrome. Antiphospholipid syndrome is an autoimmune disease that frequently manifests as recurrent arterial and/or venous thrombotic events, ischemic strokes, and miscarriages. Antiphospholipid syndrome affecting primarily the arteries is less common as compared to venous thrombosis. Our patient underwent several vascular surgical interventions and anticoagulant treatment; despite this, she ultimately underwent a below-the-knee amputation due to worsening ischemia. The purpose of the current case report is to emphasize that antiphospholipid syndrome should be kept on the differential for arterial ischemic events such as critical limb ischemia without another known cause and should be managed with an interprofessional team approach.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
128
审稿时长
6-12 weeks
期刊介绍: The Journal of the American Podiatric Medical Association, the official journal of the Association, is the oldest and most frequently cited peer-reviewed journal in the profession of foot and ankle medicine. Founded in 1907 and appearing 6 times per year, it publishes research studies, case reports, literature reviews, special communications, clinical correspondence, letters to the editor, book reviews, and various other types of submissions. The Journal is included in major indexing and abstracting services for biomedical literature.
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